DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment teq and CD5L

DIOPT Version :9

Sequence 1:	NP_648288.2	Gene:	teq / 39048	FlyBaseID:	FBgn0023479	Length:	2792	Species:	Drosophila melanogaster
Sequence 2:	XP_016858295.1	Gene:	CD5L / 922	HGNCID:	1690	Length:	353	Species:	Homo sapiens

Alignment Length:	327	Identity:	107/327 - (32%)
Similarity:	141/327 - (43%)	Gaps:	75/327 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  2229 VRLSGGESPNMGRIEVKANGQWGYVCDDKFGLKDADVVCRELGFQMGAQEVRGSSFYAPPNQDFN 2293
            |||.||.....||:||:..||||.||||.:.:||..|:|||||....:....|..:..|..::..
Human    24 VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQK 88

  Fly  2294 YLMDEVECHGNETKLGQCAFKGWGVHNCGVDEVAGVTCKVPVMK----------------CP--- 2339
            .|:..|.|.|.|..|.||..:  .|::|..||.||.:|:.|...                |.
Human    89 VLIQSVSCTGTEDTLAQCEQE--EVYDCSHDEDAGASCENPESSFSPVPEGVRLADGPGHCKGRV 151

  Fly  2340 ----NNYW---------------LCH---------TSKECIPPAF-------------------- 2356
                .|.|               :|.         |.|.|...|:
Human   152 EVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQ 216

  Fly  2357 VCDNTP---DCADKSDECAAVCQAPVQYRLEGGRNSNEGRLEVKHHGVWGSVCDDDFNLKSAQVA 2418
            .|.:.|   :..:..::....|:.|...||.||.|...|||||.|.|||||||||::..|..||.
Human   217 DCPSGPWGKNTCNHDEDTWVECEDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVV 281

  Fly  2419 CNSMG---FFGPAKIEKNIFGNSNGPIWLDQVMCFGNETSIDQCNHWNWGEHNCNHTEDVALHCS 2480
            |..:|   ...|:..::..:|...|.||||.|.|.|.|.|::||.|..||.|:|.|.||||:.||
Human   282 CKQLGCGKSLSPSFRDRKCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346

  Fly  2481 AG 2482
            .|
Human   347 GG 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
teq	NP_648288.2	CBM_14	65..115	CDD:279884
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		CBM_14	521..569	CDD:279884
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..830	CDD:279884
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:279884
		RCR	<1051..1126	CDD:304939
		RCR	<1116..1210	CDD:304939
		ChtBD2	1324..1369	CDD:214696
		ChtBD2	1474..1518	CDD:214696
		LDLa	2193..2222	CDD:238060
		SR	2229..2331	CDD:214555	41/101 (41%)
		SRCR	2234..2332	CDD:278931	37/97 (38%)
		LDLa	2337..2370	CDD:197566	10/102 (10%)
		SR	2382..2480	CDD:214555	49/100 (49%)
		SRCR	2386..2480	CDD:278931	46/96 (48%)
		Tryp_SPc	2546..2781	CDD:214473
		Tryp_SPc	2547..2784	CDD:238113
CD5L	XP_016858295.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D158600at2759
OrthoFinder	1	1.000	-	-		FOG0001772
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.920