Protein Alignment teq and LOXL4

DIOPT Version :10

• Sequence 1: NP_648288.2
• Gene: teq / 39048
• FlyBaseID: FBgn0023479
• Length: 2792
• Species: Drosophila melanogaster
• Sequence 2: XP_005270273.1
• Gene: LOXL4 / 84171
• HGNCID: 17171
• Length: 757
• Species: Homo sapiens
• Alignment Length: 665
• Identity: 156/665 - (23%)
• Similarity: 240/665 - (36%)
• Gaps: 194/665 - (29%)

  Fly  2223 PPS------DYEVRLSGGES-PNMGRIEVKANGQWGYVCDDKFGLKDADVVCRELGFQMG---AQ 2277
            |||      ..::||.|.|| |..||:||...||||.||||.|.:::|.|.||:|||:..   |.
Human    20 PPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAH 84

  Fly  2278 EVRGSSFYAPPNQDFNYLMDEVECHGNETKLGQCAFKGWGVHNCGVDEVAGVTCKVPVMKCPNNY 2342
            ..:......|      ..:|.|.|.|.|:.|.||...||||.:|...|..||.|.      |..:
Human    85 SAKYGQGEGP------IWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICH------PRRH 137

  Fly  2343 --WLCHTSKECIPPAFVCDNTPDCADKSDECAAVCQAPVQYRLEGGRNSNEGRLEVKHHGVWGSV 2405
              :|..|....:.|            :......|...|:....:......||.:|||:.|.|..|
Human   138 RGYLSETVSNALGP------------QGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQV 190

  Fly  2406 CDDDFNLKSAQVACNSMGFFGPAKIEKNIF------------------GNSNGPIWLDQVMCFGN 2452
            ||..:.:.:::|.|..:||.....::.:.:                  .|.|. .|:.||.|.|.
Human   191 CDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNS-FWIHQVTCLGT 254

  Fly  2453 ETSIDQCN------------HWNWGEHNCNHTEDVALHCSAGP---PPRSQRYSQTQIKGGRSLG 2502
            |..:..|.            ....|.|       ..:.|.|||   ||:::
Human   255 EPHMANCQVQVAPARGKLRPACPGGMH-------AVVSCVAGPHFRPPKTK-------------- 298

  Fly  2503 RETTPKTYSQIGLWERSSKAVHTPRRCGIFKDDLTDEYAHREERVVRGNVAQRGRHPWQATIRTR 2567
                                   |:|.|        .:|.:|.||...:.||.|          .
Human   299 -----------------------PQRKG--------SWAEQEPRVRLRSGAQVG----------E 322

  Fly  2568 GRGGI--SSHWCGAVVISKRHLLTAA----HCLYGSPKGAYF-VRVGDHYANIAESSEV-----D 2620
            ||..:  :..| |.|...:.:|::|:    ...:||.:.|.| .|:|.....| ..|||     :
Human   323 GRVEVLMNRQW-GTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPI-HLSEVRCRGYE 385

  Fly  2621 SFIENWYLHENFRKGTHMNNDIALVVLKTPLKFSDYVQPI--CLPDKNAELVEDRKCTISGWGSI 2683
            ..:.:....|..:.|....||.|:......:.|.:.|:..  .:|::....|:.....:..|||:
Human   386 RTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSV 450

  Fly  2684 KS---GVSTPAQV----LGSAELPILADHVCKQSNVYG------SAMSEGMFCAGSMDESVDACE 2735
            .|   |: |.|.|    ||..    .|.|..|::..:.      ..:..|:.|:|: :.::..|:
Human   451 CSENWGL-TEAMVACRQLGLG----FAIHAYKETWFWSGTPRAQEVVMSGVRCSGT-ELALQQCQ 509

  Fly  2736 GDSGGPLVCSDDDGETLYGLISWG------------QHCGF-KNRPGVYVRVNH----------Y 2777
              ..||:.||...|..|.|:....            |...: ::||...:...|          :
Human   510 --RHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADH 572

  Fly  2778 IDWIYEKINESLLRF 2792
            :||.|.  ...||||
Human   573 MDWPYG--YRRLLRF 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
teq	NP_648288.2	CBM_14	65..115	CDD:426342
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		ChtBD2	521..567	CDD:214696
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..829	CDD:426342
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:426342
		Med15	1029..>1325	CDD:312941
		ChtBD2	1324..1369	CDD:214696
		ChtBD2	1474..1518	CDD:214696
		PHA03247	<1587..1906	CDD:223021
		LDLa	2193..2222	CDD:238060
		SR	2229..2331	CDD:214555	44/105 (42%)
		LDLa	2337..2370	CDD:197566	4/34 (12%)
		SR	2382..2480	CDD:214555	25/127 (20%)
		Tryp_SPc	2547..2784	CDD:238113	61/286 (21%)
LOXL4	XP_005270273.1	SR	32..132	CDD:214555	44/105 (42%)
		SR	174..286	CDD:214555	25/119 (21%)
		SR	312..412	CDD:214555	26/111 (23%)
		SR	422..529	CDD:214555	27/114 (24%)
		Lysyl_oxidase	534..732	CDD:460102	11/54 (20%)