DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment teq and si:ch73-127m5.1

DIOPT Version :9

Sequence 1:	NP_648288.2	Gene:	teq / 39048	FlyBaseID:	FBgn0023479	Length:	2792	Species:	Drosophila melanogaster
Sequence 2:	XP_009305107.1	Gene:	si:ch73-127m5.1 / 799158	ZFINID:	ZDB-GENE-130531-25	Length:	835	Species:	Danio rerio

Alignment Length:	707	Identity:	214/707 - (30%)
Similarity:	298/707 - (42%)	Gaps:	195/707 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  2194 DCGNGQCLKKEEICDGKKNCPNGKDEANCPPSDYEVRLSGGESPNMGRIEVKANGQWGYVCDDKF 2258
            ||.:|.  :...:|:        ..|.|.||    :||.|||....||:||..:|:||.:|||::
Zfish   206 DCNHGS--EAGVVCE--------PPEGNGPP----LRLVGGEEDFEGRVEVFHDGRWGTICDDQW 256

  Fly  2259 GLKDADVVCRELG------------FQMGAQEVRGSSFYAPPNQDFNYLMDEVECHGNETKLGQC 2311
            ...||:||||:||            |..|:..::               :|.|:|.|||..|.:|
Zfish   257 DDMDAEVVCRQLGLGGIPKAWSWAHFGQGSGPIQ---------------LDAVQCTGNELSLDEC 306

  Fly  2312 AFKGWGVHNCGVDEVAGVTCKVPVMKCPNNYWLCHTSKECIPPAFVCDNTPDCADKSDECAAVCQ 2376
            ...||..|||...|.|||:|        |.|               .|..
Zfish   307 RHSGWEQHNCDHMEDAGVSC--------NPY---------------TDGV--------------- 333

  Fly  2377 APVQYRLEGGRNSNEGRLEVKHHGVWGSVCDDDFNLKSAQVACNSMGFFGPAKI-EKNIFGNSNG 2440
                .||..|.|..||||||.|...||:||||.:....|||.|..:||.|.|:: ....||...|
Zfish   334 ----VRLVDGDNPWEGRLEVYHSRDWGTVCDDSWTEPHAQVVCRQLGFRGGAEVAPAGAFGEGTG 394

  Fly  2441 PIWLDQVMCFGNETSIDQCNHWNWGEHNCNHTEDVALHC-------------SAGPPPR-----S 2487
            .|.||.|.|.|.|:|:.:|.|..||.|:|:|:|||.:.|             |.||..|     |
Zfish   395 LILLDDVECEGTESSLLECKHGVWGRHDCSHSEDVGIRCHRVENNEVPLAPESTGPLVRLAGGDS 459

  Fly  2488 QRYSQTQI----KGG----------------RSLG----RETTPKTYSQIG-------------- 2514
            ::..:.::    :.|                |.||    .:..|..|...|
Zfish   460 RKEGRVEVFLNGEWGSVCDHGWNDVNAAVVCRQLGFNGESKARPMGYFGAGKGTIHLSNVRCTGK 524

  Fly  2515 ---LWERSSK---------------------------AVHTPRRCGIFKDDLTDEYAHREERVVR 2549
               |.|..||                           ||.....||     |......|.:|:|.
Zfish   525 ESLLGECPSKGQDSHVCKHGQDAGVVCDYEPEPEADVAVVGTHTCG-----LRAGAERRSKRIVG 584

  Fly  2550 GNVAQRGRHPWQATIRTRGRGGISSHWCGAVVISKRHLLTAAHCL--YGSPKGAYFVRVGDHYAN 2612
            |..:.||..||||::..|.:...:...|||.:|:...|||||||.  :||....|.|::||::..
Zfish   585 GYKSLRGDWPWQASLWLRSQSKGNQPLCGATLINSCWLLTAAHCFKRFGSDASRYVVKLGDYHTR 649

  Fly  2613 IAESSEVDSFIENWYLHENFRKGTHMNNDIALVVLKTP----LKFSDYVQPICLPDKNAEL-VED 2672
            ..:..|.....|:..:|:.:...: ..:|:||:.||..    :.|:.:....|||...::. ...
Zfish   650 EQDDFERVLSPEHIEVHKKYHTDS-WEHDVALIRLKGTEGKCVAFNPHTNAACLPAPGSKWGKRP 713

  Fly  2673 RKCTISGWGSIKSGVSTPAQVLGSAELPILADHVCKQSNVYGSAM-SEGMFCAGSMDESV----D 2732
            ..|.|:|||  .:....|:.:| .|.:|:|....||:.  ||... |..|.|||||...:    |
Zfish   714 ASCVITGWG--MTDTEHPSTLL-QAWVPLLPSWQCKKR--YGERFTSHDMLCAGSMTSDLRKHAD 773

  Fly  2733 ACEGDSGGPLVCSDDDGE-TLYGLISWGQHCGFKNRPGVYVRVNHYIDWIYEKINES 2788
            :|:|||||||||..:.|. .|.|:||||..||..:.||||.||:.|:.|| |::..|
Zfish   774 SCQGDSGGPLVCQGEAGRWVLTGVISWGHGCGDPSYPGVYSRVSRYLGWI-EQVTHS 829

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
teq	NP_648288.2	CBM_14	65..115	CDD:279884
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		CBM_14	521..569	CDD:279884
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..830	CDD:279884
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:279884
		RCR	<1051..1126	CDD:304939
		RCR	<1116..1210	CDD:304939
		ChtBD2	1324..1369	CDD:214696
		ChtBD2	1474..1518	CDD:214696
		LDLa	2193..2222	CDD:238060	5/27 (19%)
		SR	2229..2331	CDD:214555	42/113 (37%)
		SRCR	2234..2332	CDD:278931	39/109 (36%)
		LDLa	2337..2370	CDD:197566	3/32 (9%)
		SR	2382..2480	CDD:214555	47/111 (42%)
		SRCR	2386..2480	CDD:278931	45/107 (42%)
		Tryp_SPc	2546..2781	CDD:214473	87/247 (35%)
		Tryp_SPc	2547..2784	CDD:238113	88/249 (35%)
si:ch73-127m5.1	XP_009305107.1	KR	49..112	CDD:294073
		SR	118..217	CDD:214555	3/12 (25%)
		SRCR	123..218	CDD:278931	3/13 (23%)
		SR	227..327	CDD:214555	43/122 (35%)
		SRCR	236..327	CDD:278931	38/113 (34%)
		SR	334..433	CDD:214555	46/98 (47%)
		SRCR	339..433	CDD:278931	44/93 (47%)
		SR	452..551	CDD:214555	13/98 (13%)
		SRCR	457..551	CDD:278931	12/93 (13%)
		Tryp_SPc	581..823	CDD:214473	87/247 (35%)
		Tryp_SPc	582..826	CDD:238113	89/250 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I6708
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D158600at2759
OrthoFinder	1	1.000	-	-		FOG0001772
OrthoInspector	1	1.000	-	-		otm25494
orthoMCL	1	0.900	-	-		OOG6_106745
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3236
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.820