Protein Alignment teq and DAZ2

DIOPT Version :10

• Sequence 1: NP_648288.2
• Gene: teq / 39048
• FlyBaseID: FBgn0023479
• Length: 2792
• Species: Drosophila melanogaster
• Sequence 2: NP_001376232.1
• Gene: DAZ2 / 57055
• HGNCID: 15964
• Length: 654
• Species: Homo sapiens
• Alignment Length: 609
• Identity: 161/609 - (26%)
• Similarity: 215/609 - (35%)
• Gaps: 194/609 - (31%)

  Fly   943 PPQAQGYYLHPFDCTKYIVCWEKQTHIESCPQGEAFSISQQKCVARDKITQAYDRVEYLEDTQHE 1007
            |||.|..:.:|          ..:|:::  ||.....::|.        .|||.          .
Human   136 PPQFQNVWRNP----------NTETYLQ--PQITPNPVTQH--------VQAYS----------A 170

  Fly  1008 LSHEEAE------------EEEQTEPESNLSLDGGNQPPGKYQAPYYSNGGYP----TPSQNNGG 1056
            ..|...:            :|..|.|:|...:..|      ||.|.|:...:|    :|.|...|
Human   171 YPHSPGQVITGCQLLVYNYQEYPTYPDSAFQVTTG------YQLPVYNYQPFPAYPRSPFQVTAG 229

  Fly  1057 YQTPSQNNGGYQA-------PFQNNGGYQ---------PSY-----QGNGGY-TPTYQ-NPFEGY 1098
            ||.|..|   |||       |||...|||         |:|     |...|| .|.|. ..|..|
Human   230 YQLPVYN---YQAFPAYPNSPFQVATGYQFPVYNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAY 291

  Fly  1099 HQPNQSSYQTNGGYQPPLPPHGGYQP-------PSQTYGGFQQPNRTYEDF----HNPSQTVGGF 1152
              || |.:|...|||.|:   ..|||       |.|...|:|.|...|:.|    ::|.|...|:
Human   292 --PN-SPFQVATGYQFPV---YNYQPFPAYPSSPFQVTAGYQLPVYNYQAFPAYPNSPFQVATGY 350

  Fly  1153 Q-PPYSVKGGYQ-----PHN--QLNGGYNQPNQS---------SSFQANGGYQPP---SQVNRGY 1197
            | |.|:    ||     |::  |:..||..|..:         |.||...|||.|   .|....|
Human   351 QFPVYN----YQAFPAYPNSPVQVTTGYQLPVYNYQPFPAYPRSPFQVTAGYQLPVYNYQAFPAY 411

  Fly  1198 QTS-FESNGGYQPPLETNKGHQV----PSQINGGYQPRVDGNRGY----QPPNELNGGYQPPNEL 1253
            ..| |:...|||.|:...:....    |.|:..|||..|...:.:    ..|.::..|||.|...
Human   412 PNSPFQVATGYQFPVYNYQAFPAYPNSPVQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYN 476

  Fly  1254 NGAYPA----PSQLNGGYQPPLEGNLGYRPLSQQNSGYQ--PPQPS-----TGGYQ-PPFQSTGS 1306
            ..|:||    |.|:..|||.|:             ..||  |..||     |.||| |.:.....
Human   477 YQAFPAYPSSPFQVTTGYQLPV-------------YNYQAFPAYPSSPFQVTTGYQLPVYNYQAF 528

  Fly  1307 GHYPGQDAPYAIPTPLLCPEKISGLFP----NPFD-ATGY-LTCIDGHTLPRQCQPLDVFSVSQG 1365
            ..||  .:|:.:.|....|......||    :||. .||| |...:....|  ..|...|.|:.|
Human   529 PAYP--SSPFQVTTGYQLPVYNYQAFPAYPSSPFQVTTGYQLPVYNYQAFP--AYPSSPFQVTTG 589

  Fly  1366 YCLPEQHVNKTDRVPFERTQT---YQDNSLDCPRDFLGFVVYPFDCSKYLSCGPSGMKLLNCP-G 1426
            |.||..:.......|....|.   ||            |.||.:....            .|| |
Human   590 YQLPVYNYQAFPAYPNSAVQVTTGYQ------------FHVYNYQMPP------------QCPVG 630

  Fly  1427 EQHYSI---SHGFCKPVDQVQRED 1447
            ||..::   ::.:...|..:||.|
Human   631 EQRRNLWTEAYKWWYLVCLIQRRD 654

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
teq	NP_648288.2	CBM_14	65..115	CDD:426342
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		ChtBD2	521..567	CDD:214696
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..829	CDD:426342
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:426342	9/49 (18%)
		Med15	1029..>1325	CDD:312941	111/374 (30%)
		ChtBD2	1324..1369	CDD:214696	15/50 (30%)
		ChtBD2	1474..1518	CDD:214696
		PHA03247	<1587..1906	CDD:223021
		LDLa	2193..2222	CDD:238060
		SR	2229..2331	CDD:214555
		LDLa	2337..2370	CDD:197566
		SR	2382..2480	CDD:214555
		Tryp_SPc	2547..2784	CDD:238113
DAZ2	NP_001376232.1	RRM_DAZL	35..116	CDD:410073
		PABP-1234	<40..247	CDD:130689	33/149 (22%)