DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment teq and LOC560447

DIOPT Version :9

Sequence 1:	NP_648288.2	Gene:	teq / 39048	FlyBaseID:	FBgn0023479	Length:	2792	Species:	Drosophila melanogaster
Sequence 2:	XP_021329653.1	Gene:	LOC560447 / 560447	-ID:	-	Length:	1016	Species:	Danio rerio

Alignment Length:	772	Identity:	198/772 - (25%)
Similarity:	285/772 - (36%)	Gaps:	242/772 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  2163 NDDWDLLPNSNAEEVTPKLATRSSFNT--QCDFDCGNGQCLKKEEICDGKK----NCPN-GKDEA 2220
            :||||:   ::|..|..::....:.:.  ...|..|.|:....:..|.|.:    :|.: |..|.
Zfish    62 DDDWDM---NDAAVVCRQMGCGGAVSAPQSASFGQGRGRIWLDDVRCSGSESSLTDCSHRGFGEH 123

  Fly  2221 NCPPSD--------YEVRLSGGESPNMGRIEVKANGQWGYVCDDKFGLKDADVVCRELGFQMGAQ 2277
            :|..|:        .::||.||.....||:|::.||.||.||||.:.:.||.||||::|.
Zfish   124 DCGHSEDAGVVCLVSDIRLVGGFHSCSGRVEIQYNGVWGTVCDDSWDMNDAAVVCRQMGC----- 183

  Fly  2278 EVRGSSFYAPPNQDFN-----YLMDEVECHGNETKLGQCAFKGWGVHNCGVDEVAGVTCKVPVMK 2337
               |.:..||.:..|.     ..:|:|.|.|:|:.|.||:.||:|.||||..|.|||.|
Zfish   184 ---GGAVSAPQSASFGQGSGPIWLDDVGCSGSESSLIQCSRKGFGEHNCGHSEDAGVVC------ 239

  Fly  2338 CPNNYWLCHTSKECIPPAFVCDNTPDCADKSDECAAVCQAPVQYRLEGGRNSNEGRLEVKHHGVW 2402
                                   |.|....||           .||..|.:|..||:|:.|.|.|
Zfish   240 -----------------------TQDNGKLSD-----------IRLVDGFDSCCGRVEIHHSGQW 270

  Fly  2403 GSVCDDDFNLKSAQVACNSM----GFFGPAKIEKNIFGNSNGPIWLDQVMCFGNETSIDQCNHWN 2463
            ||||||::::..|.|.|..:    ....|   ....||..:|.||||:|.|.|:|.::.||:|..
Zfish   271 GSVCDDNWDMNDAAVVCRQLQCGSAISAP---HSAAFGPGSGSIWLDEVQCTGSEGTLIQCSHDG 332

  Fly  2464 WGEHNCNHTEDVALHCS---------------------------AGPPPRSQRYSQTQI-KGGRS 2500
            .|.|||||.||..:.||                           :.|.||...|::.|: ..|.|
Zfish   333 LGRHNCNHGEDAGVVCSSELQMASLALISTHSVVSPGEIVQFRCSTPKPRCSAYAEFQLFINGSS 397

  Fly  2501 LGRET--TPKTYS-------------QIGLWERSSKA----------VHTPR--------RCGIF 2532
            |..:|  :..|:|             |......:.|:          ||.|:        ..|.|
Zfish   398 LFSQTHVSNVTFSLNVDVSHHGEYSCQYSYQNNTVKSPLSNTVTITVVHLPQPRISPSAPDGGFF 462

  Fly  2533 ----KDDLTDEYAHREERVVRGNVAQRGR------HPW-----------QATIRTRGRGGISSHW 2576
                ...||...|....|:|.||....||      ..|           .|.:..|..|
Zfish   463 FISTASALTSVTARFSLRLVNGNNDCSGRVEILYNSVWGTVCGDYWDMNDAAVVCRQMG------ 521

  Fly  2577 CGAVVISKRHLLTAAHCLYGSPKGAYF------VRVGDHYANIAESSEVDSFIENWYLHENFRK- 2634
            ||..|              .:|:.|.|      :.:.|...:.:|||..|.      .|..|.:
Zfish   522 CGGAV--------------SAPQSASFGQGSGQIWMDDVGCSGSESSLTDC------SHRGFGEH 566

  Fly  2635 --GTHMNNDIALVVLKTP-LKFSDYVQPICLPDKNAELVEDRKCTISGWGSI--------KSGVS 2688
              |.|.:..:.....|.| ::.:|.....|   ...|:::     ...|||:        .:.|.
Zfish   567 DCGHHEDAGVVCTQGKLPSIRLADGFDSCC---GRVEILQ-----YGEWGSVCDDNWDMNDAAVV 623

  Fly  2689 TPAQVLGSAELPILADHVCKQSNVYGSAMSEGMFCAGSMDESVDACEGDSGG----------PLV 2743
            ......|||   |.|.|........||...:.:.|.|| :||:..|..|..|          .:|
Zfish   624 CRQLQCGSA---ISAPHSATFGPGSGSIWLDEVNCTGS-EESLIQCSHDGLGRHNCNHGEDAGVV 684

  Fly  2744 CSDDDGETLYGLISWGQHCGFKNRPGVYV---------RVNHYIDW-IYEKINESLL 2790
            ||.:.......|||  .|....  ||..|         |.:.|.:: ::  ||.|||
Zfish   685 CSSELQMASLALIS--THSAVS--PGEIVQFRCSTPKPRCSAYAEFQLF--INGSLL 735

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
teq	NP_648288.2	CBM_14	65..115	CDD:279884
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		CBM_14	521..569	CDD:279884
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..830	CDD:279884
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:279884
		RCR	<1051..1126	CDD:304939
		RCR	<1116..1210	CDD:304939
		ChtBD2	1324..1369	CDD:214696
		ChtBD2	1474..1518	CDD:214696
		LDLa	2193..2222	CDD:238060	8/33 (24%)
		SR	2229..2331	CDD:214555	45/106 (42%)
		SRCR	2234..2332	CDD:278931	42/102 (41%)
		LDLa	2337..2370	CDD:197566	3/32 (9%)
		SR	2382..2480	CDD:214555	42/101 (42%)
		SRCR	2386..2480	CDD:278931	40/97 (41%)
		Tryp_SPc	2546..2781	CDD:214473	62/289 (21%)
		Tryp_SPc	2547..2784	CDD:238113	61/291 (21%)
LOC560447	XP_021329653.1	SR	36..136	CDD:214555	16/76 (21%)
		SR	140..240	CDD:214555	46/136 (34%)
		SR	249..349	CDD:214555	42/102 (41%)
		Ig	364..444	CDD:325142	13/79 (16%)
		SR	479..579	CDD:214555	25/125 (20%)
		SR	586..686	CDD:214555	24/111 (22%)
		Ig_2	696..781	CDD:316418	14/46 (30%)
		ig	800..866	CDD:278476
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	103	1.000	Domainoid score	I6708
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25494
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3236
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.910