DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment teq and Cd5l

DIOPT Version :9

Sequence 1:	NP_648288.2	Gene:	teq / 39048	FlyBaseID:	FBgn0023479	Length:	2792	Species:	Drosophila melanogaster
Sequence 2:	NP_033820.2	Gene:	Cd5l / 11801	MGIID:	1334419	Length:	352	Species:	Mus musculus

Alignment Length:	328	Identity:	104/328 - (31%)
Similarity:	140/328 - (42%)	Gaps:	74/328 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly  2225 SDYEVRLSGGESPNMGRIEVKANGQWGYVCDDKFGLKDADVVCRELGFQMGAQEVRGSSFYAPPN 2289
            |..:|:|.||.....||:||:.|||||.||||.:..:|..||||||......|..||:| |.||.
Mouse    23 SPTKVQLVGGAHRCEGRVEVEHNGQWGTVCDDGWDRRDVAVVCRELNCGAVIQTPRGAS-YQPPA 86

  Fly  2290 QDFNYLMDEVECHGNETKLGQCAFKGWGVHNCGVDEVAGVTCKVP-------------------- 2334
            .:...|:..|:|:|.|..|.||.. .:.|.:|..:|.||..|:.|
Mouse    87 SEQRVLIQGVDCNGTEDTLAQCEL-NYDVFDCSHEEDAGAQCENPDSDLLFIPEDVRLVDGPGHC 150

  Fly  2335 --------------VMKCPNN-------------------YWLCHTSKECIPPAFV----CD--- 2359
                          |.|...|                   |..|:.:.:...|.::    |.
Mouse   151 QGRVEVLHQSQWSTVCKAGWNLQVSKVVCRQLGCGRALLTYGSCNKNTQGKGPIWMGKMSCSGQE 215

  Fly  2360 -NTPDC--------ADKSDECAAVCQAPVQYRLEGGRNSNEGRLEVKHHGVWGSVCDDDFNLKSA 2415
             |...|        ....::....|:.|.:.:|.||.....|||||.|.|.|||||||::..|..
Mouse   216 ANLRSCLLSRLENNCTHGEDTWMECEDPFELKLVGGDTPCSGRLEVLHKGSWGSVCDDNWGEKED 280

  Fly  2416 QVACNSMG---FFGPAKIEKNIFGNSNGPIWLDQVMCFGNETSIDQCNHWNWGEHNCNHTEDVAL 2477
            ||.|..:|   ...|:...:.|:|...|.||||.|.|.|.|.|::.|.|..||.|:|.|.|||.:
Mouse   281 QVVCKQLGCGKSLHPSPKTRKIYGPGAGRIWLDDVNCSGKEQSLEFCRHRLWGYHDCTHKEDVEV 345

  Fly  2478 HCS 2480
            .|:
Mouse   346 ICT 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
teq	NP_648288.2	CBM_14	65..115	CDD:279884
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		CBM_14	521..569	CDD:279884
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..830	CDD:279884
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:279884
		RCR	<1051..1126	CDD:304939
		RCR	<1116..1210	CDD:304939
		ChtBD2	1324..1369	CDD:214696
		ChtBD2	1474..1518	CDD:214696
		LDLa	2193..2222	CDD:238060
		SR	2229..2331	CDD:214555	44/101 (44%)
		SRCR	2234..2332	CDD:278931	41/97 (42%)
		LDLa	2337..2370	CDD:197566	8/67 (12%)
		SR	2382..2480	CDD:214555	45/100 (45%)
		SRCR	2386..2480	CDD:278931	43/96 (45%)
		Tryp_SPc	2546..2781	CDD:214473
		Tryp_SPc	2547..2784	CDD:238113
Cd5l	NP_033820.2	SR	27..127	CDD:214555	44/101 (44%)
		SRCR	32..128	CDD:278931	41/97 (42%)
		SR	141..240	CDD:214555	9/98 (9%)
		SRCR	146..241	CDD:278931	9/94 (10%)
		SR	246..348	CDD:214555	45/101 (45%)
		SRCR	251..348	CDD:278931	43/96 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7291
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D158600at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010