DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment teq and LOC100911413

DIOPT Version :9

Sequence 1:	NP_648288.2	Gene:	teq / 39048	FlyBaseID:	FBgn0023479	Length:	2792	Species:	Drosophila melanogaster
Sequence 2:	XP_038957165.1	Gene:	LOC100911413 / 100911413	RGDID:	6493252	Length:	1961	Species:	Rattus norvegicus

Alignment Length:	762	Identity:	189/762 - (24%)
Similarity:	254/762 - (33%)	Gaps:	239/762 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly  1975 RPYFNHSGNAQEQLAQQAESAIVSVISKPSTTTTTTP----RPTSKTPKTDPDFDAELIKAGE-- 2033
            |.:.:|:...||.         ..||...|.|::..|    |....|..||......|:..|:
  Rat   271 RGWLSHNCGHQED---------AGVICSSSQTSSPIPDVSYRTELPTDGTDSVLAVRLVDGGDSC 326

  Fly  2034 --------QESLDSV-DDDYVFPDARETSRTEQTLDPSTTYASTNFQRSTRRAELDPDTLTA--- 2086
                    |.|..:| ||.:...||....|........:...|..|.:.:....||..:.|.
  Rat   327 RGRVEILYQGSWGTVCDDSWDINDANVVCRQLGCGGALSAPGSDQFGQGSGSIVLDEVSCTGHEA 391

  Fly  2087 ---TTMKTNW--HAPGHSRD----------------------YHRRHPNLPDPFTEHHPNSSPHQ 2124
               ......|  |..||..|                      .|.....:.:..||....|||..
  Rat   392 YLWNCSHQGWLSHNCGHQEDAGVVCSASQTSSPTPGLWNPRGTHNDVVYVTEETTEASQTSSPTP 456

  Fly  2125 HHHHHRHPH--------EHSADFHIRHPELP---NPFPLKNETPQHQDLNDDWDLLPNSNAEEVT 2178
            ...:.|..|        |.:.|.....| .|   ||....|.|...|        :|:|.:....
  Rat   457 GLWNPRGTHNDVVYVTEETTEDSQTSSP-TPGWWNPGGTPNVTSSTQ--------VPDSTSIGTD 512

  Fly  2179 PKLATR-----------------SSFNTQCD----------------------------FDCGNG 2198
            ..||.|                 .|:.|.||                            |..|:|
  Rat   513 SVLAVRLVNGGDRCRGRVEIFYQGSWGTVCDDSWDINDANVVCRQLGCGGALSAPGSDQFGQGSG 577

  Fly  2199 QCLKKEEICDGKK--------------NCPNGKDE-ANCPPSD--YEVRLSGGESPNMGRIEVKA 2246
            ..:..|..|.|.:              ||.:.:|. ..|..:|  ..|||..|.:...||:|:..
  Rat   578 SIVLDEVACTGNETYLWNCSHRGWLSHNCDHQEDAGVICSGTDSVLAVRLVNGGNSCRGRVEILY 642

  Fly  2247 NGQWGYVCDDKFGLKDADVVCRELGFQMGAQEVRGSSFYAPPNQDF-----NYLMDEVECHGNET 2306
            .|.||.||||.:.:.||:||||:||.        |.:..||.:..|     :.::|||.|.||||
  Rat   643 QGSWGTVCDDSWDINDANVVCRQLGC--------GGALSAPGSDQFGQGSGSIVLDEVACTGNET 699

  Fly  2307 KLGQCAFKGWGVHNCGVDEVAGVTCKVPVMKCPNNYWLCHTSKECIPPAFVCDNTPDCADKSDEC 2371
            .|..|:.:||..|||...|.|||                           :|..|       |..
  Rat   700 YLWNCSHRGWLSHNCDHQEDAGV---------------------------ICSGT-------DSG 730

  Fly  2372 AAVCQAPVQYRLEGGRNSNEGRLEVKHHGVWGSVCDDDFNLKSAQVACNSMGFFGPAKIE-KNIF 2435
            .||       ||..|.::..||:|:.:.|.||:||||.:::..|.|.|..:|..|..... .:.|
  Rat   731 LAV-------RLVNGGDTCRGRVEILYQGSWGTVCDDSWDINDANVVCRQLGCGGALSAPGSDQF 788

  Fly  2436 GNSNGPIWLDQVMCFGNETSIDQCNHWNWGEHNCNHTEDVALHCSAGPPPRSQRYSQTQ------ 2494
            |..:|.|.||:|.|.|:|..:..|.|..|..|||.|.||..:.|||     ||..|.|.
  Rat   789 GQGSGSIVLDEVSCTGHEAYLWNCTHRGWLSHNCGHQEDAGVICSA-----SQTSSPTPDVSYRT 848

  Fly  2495 ---------------IKGG-RSLGRETTPKTYSQIGLWE---------RSSKAVHTPRRC-GIFK 2533
                           :.|| |..||  ....|.  |.|.         ..:|.|.....| |...
  Rat   849 ELPTDGTDSVLAVRLVNGGDRCRGR--VEILYQ--GSWGTVCDDSWDINDAKVVCRQLGCGGALS 909

  Fly  2534 DDLTDEYAHREERVVRGNVAQRGR--HPWQATIRTRGRGGISSHWCG 2578
            ...:|::......:|...||..|.  :.|..|.|     |..||.||
  Rat   910 APGSDQFGQGSGSIVLDEVACTGHEAYLWNCTHR-----GWLSHNCG 951

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
teq	NP_648288.2	CBM_14	65..115	CDD:279884
		ChtBD2	136..184	CDD:214696
		ChtBD2	215..261	CDD:214696
		ChtBD2	284..327	CDD:214696
		CBM_14	521..569	CDD:279884
		ChtBD2	608..654	CDD:214696
		ChtBD2	709..752	CDD:214696
		CBM_14	782..830	CDD:279884
		ChtBD2	864..909	CDD:214696
		CBM_14	942..993	CDD:279884
		RCR	<1051..1126	CDD:304939
		RCR	<1116..1210	CDD:304939
		ChtBD2	1324..1369	CDD:214696
		ChtBD2	1474..1518	CDD:214696
		LDLa	2193..2222	CDD:238060	9/43 (21%)
		SR	2229..2331	CDD:214555	45/106 (42%)
		SRCR	2234..2332	CDD:278931	42/102 (41%)
		LDLa	2337..2370	CDD:197566	2/32 (6%)
		SR	2382..2480	CDD:214555	37/98 (38%)
		SRCR	2386..2480	CDD:278931	35/94 (37%)
		Tryp_SPc	2546..2781	CDD:214473	12/35 (34%)
		Tryp_SPc	2547..2784	CDD:238113	12/34 (35%)
LOC100911413	XP_038957165.1	SR	81..181	CDD:214555
		SR	189..289	CDD:214555	6/26 (23%)
		SR	317..417	CDD:214555	20/99 (20%)
		SR	517..617	CDD:214555	14/99 (14%)
		SR	625..725	CDD:214555	45/134 (34%)
		SR	733..833	CDD:214555	38/106 (36%)
		SR	861..961	CDD:214555	25/100 (25%)
		SR	978..1078	CDD:214555
		CUB	1271..1379	CDD:238001
		SR	1394..1494	CDD:214555
		CUB	1509..1617	CDD:238001
		ZP	1628..1875	CDD:214579
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7126
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D90326at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010