DRSC/TRiP Functional Genomics Resources

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Protein Alignment OR4Q2 and npr-19

DIOPT Version :9

Sequence 1:NP_001335200.1 Gene:OR4Q2 / 390432 HGNCID:15359 Length:313 Species:Homo sapiens
Sequence 2:NP_508147.2 Gene:npr-19 / 182130 WormBaseID:WBGene00015364 Length:420 Species:Caenorhabditis elegans


Alignment Length:335 Identity:69/335 - (20%)
Similarity:127/335 - (37%) Gaps:87/335 - (25%)


- Green bases have known domain annotations that are detailed below.


Human    33 FFYMSIW--------VGNVLIMVTVASDKYLNSSPMYFLLGNLSFLDLCYSTVTTPKLLADFFNH 89
            |..:|||        :.|:||:..:|....:.|:..|:.:.:::..|:..:.::...|:.....|
 Worm    29 FIAVSIWTIMLLYALISNMLILAGIARSSTMRSATSYWFIISIAICDILMTFISLGHLVPATAFH 93

Human    90 EKLISYDQC--IVQLFFLHFVGAAEMFLLTVMAYDRYVAICRPLHYTTVMSQGLCCVLVAASWMG 152
            |:.:.:...  ||.:||........:..|.:||.:|:|:|..|:.|..:.|:.....|:...:..
 Worm    94 EEYVQFKSIRNIVMIFFYDLFWYTGVVQLGLMAGNRFVSIVYPMEYKHIFSRTRSLYLILFGYFL 158

Human   153 GFVHSTVQTILTVHLP----FCGPNQVENFFCDV--PPVIKLACADTFVIELLMVSNSGLISTIS 211
            ||:         |.||    .|......|::..|  .|       ||....:.|..||     ||
 Worm   159 GFL---------VSLPTLFDCCHTLWDSNYYITVYEKP-------DTLYKYVDMAVNS-----IS 202

Human   212 FVVLISSYTTILVKIRSKEGRRKA-----------------------LSTCASHLMV-------- 245
            ..::|.||..|::|:|: .||..|                       :|.|.....|        
 Worm   203 LCMMIISYAVIILKVRA-SGRAMAKYQLTIRTRQQNALVNGVSLSCQMSECGRTSSVRPPRSQVS 266

Human   246 -------VTLFFGPCIFIYA------RPF---STFSVDKMVSVLYNVITPMLNPLIYTLRNKEVK 294
                   :..|....:|:..      .|:   |.::...|.|:.:  |...:||.:|.:.|.:::
 Worm   267 KKEMRLFIQFFVVSLVFLLTWTTWQWLPYMSESKWAYFVMTSLFF--INNSVNPTVYIIFNTQLR 329

Human   295 SAMQKLWVRN 304
            ..:..|..|:
 Worm   330 RELHYLICRH 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
OR4Q2NP_001335200.1 7tmA_OR4Q2-like 25..290 CDD:320604 66/319 (21%)
TM helix 1 26..52 CDD:320604 8/26 (31%)
TM helix 2 60..86 CDD:320604 3/25 (12%)
TM helix 3 98..128 CDD:320604 9/31 (29%)
TM helix 4 141..162 CDD:320604 3/20 (15%)
TM helix 5 196..226 CDD:320604 9/29 (31%)
TM helix 6 230..260 CDD:320604 8/73 (11%)
TM helix 7 265..290 CDD:320604 6/24 (25%)
npr-19NP_508147.2 7tm_classA_rhodopsin-like 32..325 CDD:381740 65/316 (21%)
TM helix 1 32..55 CDD:381740 6/22 (27%)
TM helix 2 64..89 CDD:381740 3/24 (13%)
TM helix 3 105..127 CDD:381740 6/21 (29%)
TM helix 4 150..166 CDD:381740 5/24 (21%)
TM helix 5 192..211 CDD:381740 7/23 (30%)
TM helix 6 270..291 CDD:381740 2/20 (10%)
TM helix 7 300..325 CDD:381740 6/26 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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