DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment OR4Q2 and or70a13

DIOPT Version :9

Sequence 1:	NP_001335200.1	Gene:	OR4Q2 / 390432	HGNCID:	15359	Length:	313	Species:	Homo sapiens
Sequence 2:	NP_001122057.1	Gene:	or70a13 / 100151263	ZFINID:	ZDB-GENE-070806-11	Length:	314	Species:	Danio rerio

Alignment Length:	301	Identity:	95/301 - (31%)
Similarity:	166/301 - (55%)	Gaps:	9/301 - (2%)

- Green bases have known domain annotations that are detailed below.

Human    14 LSGFSQTPSIEAGLFVLFLFFYMSIWVGNVLIMVTVASDKYLNSSPMYFLLGNLSFLDLCYSTVT 78
            :.|...|......:|::....|:...:.|:.::..::::|.|: .||:||..||...|:..:||.
Zfish    13 VEGLKVTHQSSQPVFIVLFLSYIFAMISNITLIFLISTEKNLH-DPMHFLFCNLPVNDIIGTTVI 76

Human    79 TPKLLADFFNH--EKLISYDQCIVQLFFLHFVGAAEMFLLTVMAYDRYVAICRPLHYTTVMSQGL 141
            .|:|:.|....  |:.|||.:|:||.:|:|...||..::|.:||:|||||||.||.||.:|:..:
Zfish    77 LPRLMQDVLKEASERYISYTECVVQAYFVHVFTAACHYVLMIMAFDRYVAICNPLRYTAIMTNKM 141

Human   142 CCVLVAASWMGGFVHSTVQTILTVHLPFCGPNQVENFFCDVPPVIKLACADTFVIELLMVSNSGL 206
            ...|.|::|....:..||...||:.|..| .:.:||.|||...:.||:|.:..:.....|..|.:
Zfish   142 VIKLSASAWGLAIIVVTVMIGLTLRLSHC-RSTIENPFCDNASLFKLSCENVSINNAFGVVYSVI 205

Human   207 ISTISFVVLISSY---TTILVKIRSKEGRRKALSTCASHLMV-VTLFFGPCIFIYARPFSTFSVD 267
            ::.:|.:.:..:|   .|:.:..::|....||:.||::||.| :.:|....|||:...|..::..
Zfish   206 VACLSAISIFITYVKIATVCLASKNKALNSKAMKTCSTHLAVYLIMFVSGAIFIFLHRFPEYAES 270

Human   268 -KMVSVLYNVITPMLNPLIYTLRNKEVKSAMQKLWVRNGLT 307
             |:.|::::::.|.||||:|.|:.||::....||..|...|
Zfish   271 RKLGSIMFHIVPPGLNPLVYGLQTKEIRQRFVKLCRRKTST 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
OR4Q2	NP_001335200.1	7tmA_OR4Q2-like	25..290	CDD:320604	87/271 (32%)
		TM helix 1	26..52	CDD:320604	3/25 (12%)
		TM helix 2	60..86	CDD:320604	10/25 (40%)
		TM helix 3	98..128	CDD:320604	15/29 (52%)
		TM helix 4	141..162	CDD:320604	5/20 (25%)
		TM helix 5	196..226	CDD:320604	5/32 (16%)
		TM helix 6	230..260	CDD:320604	11/30 (37%)
		TM helix 7	265..290	CDD:320604	9/25 (36%)
or70a13	NP_001122057.1	7tm_4	32..304	CDD:304433	88/273 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910