DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4911 and FipoQ

DIOPT Version :9

Sequence 1:	NP_001286990.1	Gene:	CG4911 / 39043	FlyBaseID:	FBgn0035959	Length:	450	Species:	Drosophila melanogaster
Sequence 2:	NP_733291.1	Gene:	FipoQ / 43475	FlyBaseID:	FBgn0039667	Length:	515	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	87/483 - (18%)
Similarity:	159/483 - (32%)	Gaps:	187/483 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 RIPSVALNHIFDYLNPQDRRSAAGVCFSWRHALFQKRYFRNFRFQLDVGCDDQLAFFHRSMANLA 76
            ::|...|.|||.||:.::....|.:|..||...:..|.::|      |....:::..|.....:.
  Fly    36 KLPDKVLLHIFSYLSHREICRLARICRRWRQIAYDTRLWKN------VSLRPEVSGLHVGSLEML 94

  Fly    77 MELIVVFDFQNAVHIQ-KMRGLLYKVAH-----CDNIQKLRFQTHNVGLVAIGNMHSEHLLAIEQ 135
            ::||.|.......:|: .:..:.:.|.|     |.|:      ||
  Fly    95 LQLISVRFGPTLRYIELPIELITHTVLHELSAKCPNL------TH-------------------- 133

  Fly   136 CFVEPLILFLSRKRQPCQLLDLGAIEALSYYGHDFLKAMGKPQELLQLTLASIKYDPSHYPILSL 200
                             .|||......|    |||.:....|.:|             .|..:.|
  Fly   134 -----------------MLLDFSTAMQL----HDFSEMQAFPTKL-------------RYMCVCL 164

  Fly   201 DSTLLQK---------CAALQVLSL--DYDTLSDELLHTIQVLPLRKL--------LIAVHGLD- 245
            ...:..:         ...|:||.|  .|:...:|.....:|:.:.||        :|.::|::
  Fly   165 SEVIFMEGFMRKIYNFINGLEVLHLIGTYEKCEEEEEEIYEVINVHKLKSATPNLRVINLYGINF 229

  Fly   246 -SEEHPDVSETAWSNFSDHFSS--IELVLTLVYAYEAIALLQHRVLRSNMPVTHVRLLFCEKMNA 307
             .:.|.|.           |||  |:|        |.:|                 :.||.|:..
  Fly   230 IDDSHIDA-----------FSSNCIQL--------ECLA-----------------VNFCNKVTG 258

  Fly   308 EALDWMSLHYRETLRSIHYVDAPYKYSNRMNSSRRVSL-------LQDPFVMMA-WRCKQLEEIV 364
                       .||:::            :..|:|::.       |:..|||.| |....|:|:.
  Fly   259 -----------STLKTL------------IQRSKRLTCLLMNGTSLKSEFVMQAEWDKCALQELD 300

  Fly   365 VHGYLMDPHNLVGIARLRGRQLKRLEVSMIDWSGAPLLNAYNEEISTLLGQQW-------SPISF 422
            :....:....||.:       |.|  :..:.:..|..:|.:|:.:.    :||       |.||.
  Fly   301 ITATDLSTECLVDM-------LSR--IPSLKFLSAGQINGFNDSVL----KQWMESGTTRSLISL 352

  Fly   423 DKMPPSLFYDNDLRDQFVYEMLRQDLRQ 450
            |     |...:::.|:.:.:.:::...|
  Fly   353 D-----LDSSDNISDEGLLKFIQRQGHQ 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4911	NP_001286990.1	F-box	8..53	CDD:279040	12/40 (30%)
FipoQ	NP_733291.1	F-box-like	34..80	CDD:289689	14/49 (29%)
		leucine-rich repeat	131..156	CDD:275381	10/71 (14%)
		leucine-rich repeat	157..175	CDD:275381	3/30 (10%)
		leucine-rich repeat	219..244	CDD:275381	7/35 (20%)
		leucine-rich repeat	245..270	CDD:275381	9/72 (13%)
		leucine-rich repeat	271..295	CDD:275381	6/23 (26%)
		leucine-rich repeat	296..320	CDD:275381	6/32 (19%)
		leucine-rich repeat	321..348	CDD:275381	5/30 (17%)
		leucine-rich repeat	349..375	CDD:275381	5/30 (17%)
		leucine-rich repeat	376..403	CDD:275381	87/483 (18%)
		leucine-rich repeat	405..432	CDD:275381
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR20933
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100