DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Argk and ckmt1

DIOPT Version :9

Sequence 1:	NP_729446.1	Gene:	Argk / 39041	FlyBaseID:	FBgn0000116	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_942096.1	Gene:	ckmt1 / 321892	ZFINID:	ZDB-GENE-030131-611	Length:	417	Species:	Danio rerio

Alignment Length:	342	Identity:	143/342 - (41%)
Similarity:	209/342 - (61%)	Gaps:	15/342 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   232 LKKYLTKEVFDNLKNKVTPTFKSTLLDVIQSGLEN--HD--SGVGIYAPDAEAYTVFADLFDPII 292
            :..:||..|:..|.:|.||. ..||.:.||:|::|  |.  ..||:.|.|.|:|.||||:|:|:|
Zfish    64 MASHLTPAVYAKLCDKSTPN-GYTLDEAIQTGVDNPGHPFIKTVGMVAGDEESYEVFADIFNPVI 127

  Fly   293 EDYHGGFKKTD-KHPASNFGDVSTFGNVDPTNEYVISTRVRCGRSMQGYPFNPCLTEAQYKEMES 356
            ::.|.|:...: |||..........|..|  .:||:|:|||.|||::|....|..|.|:.:|:|.
Zfish   128 KERHNGYDPCNMKHPTDLDSSKIRGGMFD--EKYVLSSRVRTGRSIRGLSLPPACTRAERREVER 190

  Fly   357 KVSSTLSGLEGELKGKFYPLTGMEKAVQQQLIDDHFLF-KEGDRFLQAANACRFWPSGRGIYHND 420
            .|...|:||:|:|.||:|.||.|.:..||||||||||| |.....|..|...|.||..|||:||:
Zfish   191 VVVDALAGLKGDLTGKYYSLTVMTEQEQQQLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNN 255

  Fly   421 AKTFLVWCNEEDHLRIISMQQGGDLGQIYKRLVTAVNEIEKRV-----PFSHDDRLGFLTFCPTN 480
            .||||||.|||||.|:|||::||::.::::|....:.|:|:.:     .|..::|||::..||:|
Zfish   256 EKTFLVWINEEDHTRVISMEKGGNMRRVFERFCKGLQEVERLIQEKGWEFMWNERLGYILTCPSN 320

  Fly   481 LGTTIRASVHIKVPKLASNKAKLEEVAAKYNLQVRGTRGEHTEAEGGVYDISNKRRMGLTEFEAV 545
            |||.:||.||:.:|:| |...:..::.....||.|||.|..|.|.|..:||||..|:|.:|.:.|
Zfish   321 LGTGLRAGVHVNLPRL-SKDPRFSKILDNLRLQKRGTGGVDTAAVGSTFDISNLDRLGQSEVQLV 384

  Fly   546 KEMYDGITELIKLEKSL 562
            :.:.||:..||:.|:.|
Zfish   385 QTVIDGVNYLIECERKL 401

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Argk	NP_729446.1	arginine_kinase_like	215..562	CDD:153079	142/340 (42%)
ckmt1	NP_942096.1	creatine_kinase_like	50..407	CDD:153076	143/342 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I3023
eggNOG	1	0.900	-	-		E1_COG3869
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2808
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287050at33208
OrthoFinder	1	1.000	-	-		FOG0000437
OrthoInspector	1	1.000	-	-		mtm6403
orthoMCL	1	0.900	-	-		OOG6_100675
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2592
SonicParanoid	1	1.000	-	-		X315
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.760