DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Argk and Ckm

DIOPT Version :9

Sequence 1:	NP_729446.1	Gene:	Argk / 39041	FlyBaseID:	FBgn0000116	Length:	562	Species:	Drosophila melanogaster
Sequence 2:	NP_036662.1	Gene:	Ckm / 24265	RGDID:	2358	Length:	381	Species:	Rattus norvegicus

Alignment Length:	359	Identity:	161/359 - (44%)
Similarity:	226/359 - (62%)	Gaps:	17/359 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   215 KLEEGYAKLAASDSKSLLKKYLTKEVFDNLKNKVTPTFKSTLLDVIQSGLEN--HD--SGVGIYA 275
            |.:|.|..|  |...:.:.|.||.::::.|::|.||: ..||.||||:|::|  |.  ..||..|
  Rat    15 KSQEEYPDL--SKHNNHMAKVLTPDLYNKLRDKETPS-GFTLDDVIQTGVDNPGHPFIMTVGCVA 76

  Fly   276 PDAEAYTVFADLFDPIIEDYHGGFKKTDKHPAS-NFGDVSTFGNVDPTNEYVISTRVRCGRSMQG 339
            .|.|:||||.|||||||:|.|||||.||||... |..::....::||  .||:|:|||.|||::|
  Rat    77 GDEESYTVFKDLFDPIIQDRHGGFKPTDKHKTDLNHENLKGGDDLDP--NYVLSSRVRTGRSIKG 139

  Fly   340 YPFNPCLTEAQYKEMESKVSSTLSGLEGELKGKFYPLTGMEKAVQQQLIDDHFLF-KEGDRFLQA 403
            |...|..:..:.:.:|......|:.|.||.|||:|||..|.:..||||||||||| |.....|.|
  Rat   140 YTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEQEQQQLIDDHFLFDKPVSPLLLA 204

  Fly   404 ANACRFWPSGRGIYHNDAKTFLVWCNEEDHLRIISMQQGGDLGQIYKRLVTAVNEIE---KRV-- 463
            :...|.||..|||:|||.|:||||.|||||||:|||::||::.::::|....:.:||   |:.
  Rat   205 SGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAGH 269

  Fly   464 PFSHDDRLGFLTFCPTNLGTTIRASVHIKVPKLASNKAKLEEVAAKYNLQVRGTRGEHTEAEGGV 528
            ||..::.||::..||:||||.:|..||:|:..| |...|.||:..:..||.|||.|..|.|.|.|
  Rat   270 PFMWNEHLGYVLTCPSNLGTGLRGGVHVKLANL-SKHPKFEEILTRLRLQKRGTGGVDTAAVGAV 333

  Fly   529 YDISNKRRMGLTEFEAVKEMYDGITELIKLEKSL 562
            :||||..|:|.:|.|.|:.:.||:..::::||.|
  Rat   334 FDISNADRLGSSEVEQVQLVVDGVKLMVEMEKKL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Argk	NP_729446.1	arginine_kinase_like	215..562	CDD:153079	160/357 (45%)
Ckm	NP_036662.1	creatine_kinase_like	16..373	CDD:153076	160/358 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341349
Domainoid	1	1.000	197	1.000	Domainoid score	I3004
eggNOG	1	0.900	-	-		E1_COG3869
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2802
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D287050at33208
OrthoFinder	1	1.000	-	-		FOG0000437
OrthoInspector	1	1.000	-	-		mtm9032
orthoMCL	1	0.900	-	-		OOG6_100675
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X315
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.660