DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5144 and ckmt2b

DIOPT Version :9

Sequence 1:	NP_648284.1	Gene:	CG5144 / 39040	FlyBaseID:	FBgn0035957	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_956991.1	Gene:	ckmt2b / 799492	ZFINID:	ZDB-GENE-040426-1654	Length:	413	Species:	Danio rerio

Alignment Length:	356	Identity:	140/356 - (39%)
Similarity:	209/356 - (58%)	Gaps:	38/356 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 LKKH-------LTKEIFEKLKTKTTPSFNSTLLHCISSGMCN--HD--SGVGLYAPDPEAYKVFA 108
            |:||       ||..|:.:|:.|.||: |.::..||.:|:.|  |.  ..||:.|.|.|:|:|||
Zfish    52 LRKHNNCMASALTPAIYGRLRDKLTPN-NWSVDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFA 115

  Fly   109 DLFDPVIEEYHKCF-KKTDKQPATAFGKGADFENLDP--------DGHFIVSTRVRCGRAVKGYP 164
            |||||||::.|..: .||.|.|.          :||.        |..:::|:|||.||:::|..
Zfish   116 DLFDPVIKDRHNGYDPKTMKHPT----------DLDSSKITNGMFDEKYVLSSRVRTGRSIRGLS 170

  Fly   165 FNPCLTEADYMELESKICGAVTSLTGEYKGKYMPLTGMDKCIQEQLIEDHYLF-KEGDRFLASAG 228
            ..|..:.|:..|:|.....|::.|..:..|||..||.|.:..|:|||::|:|| |.....|.::|
Zfish   171 LPPACSRAERREVERVTVQALSGLKDDLAGKYYSLTEMTEQEQQQLIDEHFLFDKPVSPLLTASG 235

  Fly   229 ASRYWPTGRGIFLNSAKNFLVWCNEEDHIRIISMEKGGDLGKVYDRMVGGVEALGKQL-----QF 288
            .:|.||..|||:.|:.|.||:|.|||||.|:|||||||::.:|::|...|::.:.:.:     :|
Zfish   236 MARDWPDARGIWHNNEKTFLIWINEEDHTRVISMEKGGNMQRVFERFCRGLKEVERLIEERGWEF 300

  Fly   289 NRDERLGFLTFCPTNLGTSIRASVHIKLPNLMCDPDEMKKLADKYRLQIRGTSGEHSEAKGGVHD 353
            ..:||||::..||:||||.:||.||::||.|..| ....|:.|..|||.|||.|..:.|.|...|
Zfish   301 MWNERLGYILTCPSNLGTGLRAGVHVRLPILSKD-KRFNKILDNLRLQKRGTGGVDTAAVGDTFD 364

  Fly   354 ISNQRRMGLTEYEIIKEMHDGIKGLIEAECK 384
            |||..|:|.:|.|:::.:.||:..||:.|.|
Zfish   365 ISNLDRLGKSEVELVQCVVDGVNYLIDCEKK 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5144	NP_648284.1	arginine_kinase_like	40..382	CDD:153079	138/352 (39%)
ckmt2b	NP_956991.1	creatine_kinase_like	45..402	CDD:153076	140/356 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I3023
eggNOG	1	0.900	-	-		E1_COG3869
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2808
OMA	1	1.010	-	-		QHG58958
OrthoDB	1	1.010	-	-		D287050at33208
OrthoFinder	1	1.000	-	-		FOG0000437
OrthoInspector	1	1.000	-	-		mtm6403
orthoMCL	1	0.900	-	-		OOG6_100675
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X315
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.740