Protein Alignment Argk2 and Ckmt2

DIOPT Version :10

• Sequence 1: NP_648284.1
• Gene: Argk2 / 39040
• FlyBaseID: FBgn0035957
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_940807.1
• Gene: Ckmt2 / 76722
• MGIID: 1923972
• Length: 419
• Species: Mus musculus
• Alignment Length: 412
• Identity: 152/412 - (36%)
• Similarity: 223/412 - (54%)
• Gaps: 60/412 - (14%)

  Fly    13 LLGRCAQL--------------VINRHASKGNVDKEVMEQMEKGYKKLAESKSKSLLKKH----- 58
            |.||.|.|              ::||.    .|..:..||    :|....|.....|:||
Mouse     9 LTGRNASLLFTTLGTSALTTGYLLNRQ----KVSADAREQ----HKLFPPSADYPDLRKHNNCMA 65

  Fly    59 --LTKEIFEKLKTKTTPSFNSTLLHCISSGMCN--HD--SGVGLYAPDPEAYKVFADLFDPVIEE 117
              ||..|:.||:.|.||| ..||..||.:|:.|  |.  ..||:.|.|.|:|:||||||||||:.
Mouse    66 ECLTPTIYAKLRNKMTPS-GYTLDQCIQTGVDNPGHPFIKTVGMVAGDEESYEVFADLFDPVIKL 129

  Fly   118 YHKCF-KKTDKQPATAFGKGADFENLDP--------DGHFIVSTRVRCGRAVKGYPFNPCLTEAD 173
            .|..: .:..|.|.          :||.        |..:::|:|||.||:::|....|..:.|:
Mouse   130 RHNGYDPRVMKHPT----------DLDASKITHGQFDERYVLSSRVRTGRSIRGLSLPPACSRAE 184

  Fly   174 YMELESKICGAVTSLTGEYKGKYMPLTGMDKCIQEQLIEDHYLF-KEGDRFLASAGASRYWPTGR 237
            ..|:|:....|:..|.|:..|:|..|:.|.:..|::||:||:|| |.....|..||.:|.||..|
Mouse   185 RREVENVAITALEGLKGDLAGRYYKLSEMTEQDQQRLIDDHFLFDKPVSPLLTCAGMARDWPDAR 249

  Fly   238 GIFLNSAKNFLVWCNEEDHIRIISMEKGGDLGKVYDRMVGGVEALGKQLQ-----FNRDERLGFL 297
            ||:.|..|.||:|.|||||.|:|||||||::.:|::|...|::.:.:.:|     |..:||||::
Mouse   250 GIWHNYDKTFLIWINEEDHTRVISMEKGGNMKRVFERFCRGLKEVERLIQERGWEFMWNERLGYI 314

  Fly   298 TFCPTNLGTSIRASVHIKLPNLMCDPDEMKKLADKYRLQIRGTSGEHSEAKGGVHDISNQRRMGL 362
            ..||:||||.:||.||:::|.|..|| ...|:.:..|||.|||.|..:.|...|:||||..|:|.
Mouse   315 LTCPSNLGTGLRAGVHVRIPKLSKDP-RFSKILENLRLQKRGTGGVDTAAVADVYDISNIDRIGR 378

  Fly   363 TEYEIIKEMHDGIKGLIEAECK 384
            :|.|:::.:.||:..|::.|.|
Mouse   379 SEVELVQIVIDGVNYLVDCEKK 400

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Argk2	NP_648284.1	arginine_kinase_like	40..382	CDD:153079	140/367 (38%)
Ckmt2	NP_940807.1	Cardiolipin-binding. /evidence=ECO:0000250	40..64		7/27 (26%)
		creatine_kinase_like	50..407	CDD:153076	141/363 (39%)