DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5144 and ckmt1

DIOPT Version :9

Sequence 1:	NP_648284.1	Gene:	CG5144 / 39040	FlyBaseID:	FBgn0035957	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_942096.1	Gene:	ckmt1 / 321892	ZFINID:	ZDB-GENE-030131-611	Length:	417	Species:	Danio rerio

Alignment Length:	397	Identity:	154/397 - (38%)
Similarity:	224/397 - (56%)	Gaps:	37/397 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LQLLGRCAQLV---INR--HASKGNVDKEVMEQMEKGYKKLAE----SKSKSLLKKHLTKEIFEK 66
            |.|:|..:..|   :||  |.|.|:..:.:       |...||    .|..:.:..|||..::.|
Zfish    18 LSLVGAGSLTVGFFLNREQHVSAGSSVRRI-------YPPSAEYPDLRKHNNCMASHLTPAVYAK 75

  Fly    67 LKTKTTPSFNSTLLHCISSGMCN--HD--SGVGLYAPDPEAYKVFADLFDPVIEEYHKCFKKTDK 127
            |..|:||: ..||...|.:|:.|  |.  ..||:.|.|.|:|:||||:|:|||:|.|..:...:.
Zfish    76 LCDKSTPN-GYTLDEAIQTGVDNPGHPFIKTVGMVAGDEESYEVFADIFNPVIKERHNGYDPCNM 139

  Fly   128 QPATAFG----KGADFENLDPDGHFIVSTRVRCGRAVKGYPFNPCLTEADYMELESKICGAVTSL 188
            :..|...    :|..|     |..:::|:|||.||:::|....|..|.|:..|:|..:..|:..|
Zfish   140 KHPTDLDSSKIRGGMF-----DEKYVLSSRVRTGRSIRGLSLPPACTRAERREVERVVVDALAGL 199

  Fly   189 TGEYKGKYMPLTGMDKCIQEQLIEDHYLF-KEGDRFLASAGASRYWPTGRGIFLNSAKNFLVWCN 252
            .|:..|||..||.|.:..|:|||:||:|| |.....|..||.:|.||..|||:.|:.|.||||.|
Zfish   200 KGDLTGKYYSLTVMTEQEQQQLIDDHFLFDKPVSPLLTCAGMARDWPDARGIWHNNEKTFLVWIN 264

  Fly   253 EEDHIRIISMEKGGDLGKVYDRMVGGVEALGKQLQ-----FNRDERLGFLTFCPTNLGTSIRASV 312
            ||||.|:|||||||::.:|::|...|::.:.:.:|     |..:||||::..||:||||.:||.|
Zfish   265 EEDHTRVISMEKGGNMRRVFERFCKGLQEVERLIQEKGWEFMWNERLGYILTCPSNLGTGLRAGV 329

  Fly   313 HIKLPNLMCDPDEMKKLADKYRLQIRGTSGEHSEAKGGVHDISNQRRMGLTEYEIIKEMHDGIKG 377
            |:.||.|..|| ...|:.|..|||.|||.|..:.|.|...||||..|:|.:|.::::.:.||:..
Zfish   330 HVNLPRLSKDP-RFSKILDNLRLQKRGTGGVDTAAVGSTFDISNLDRLGQSEVQLVQTVIDGVNY 393

  Fly   378 LIEAECK 384
            |||.|.|
Zfish   394 LIECERK 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5144	NP_648284.1	arginine_kinase_like	40..382	CDD:153079	143/359 (40%)
ckmt1	NP_942096.1	creatine_kinase_like	50..407	CDD:153076	144/358 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	198	1.000	Domainoid score	I3023
eggNOG	1	0.900	-	-		E1_COG3869
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	288	1.000	Inparanoid score	I2808
OMA	1	1.010	-	-		QHG58958
OrthoDB	1	1.010	-	-		D287050at33208
OrthoFinder	1	1.000	-	-		FOG0000437
OrthoInspector	1	1.000	-	-		mtm6403
orthoMCL	1	0.900	-	-		OOG6_100675
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X315
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.740