DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5144 and Ckmt1

DIOPT Version :9

Sequence 1:	NP_648284.1	Gene:	CG5144 / 39040	FlyBaseID:	FBgn0035957	Length:	388	Species:	Drosophila melanogaster
Sequence 2:	NP_001341998.1	Gene:	Ckmt1 / 12716	MGIID:	99441	Length:	418	Species:	Mus musculus

Alignment Length:	348	Identity:	142/348 - (40%)
Similarity:	209/348 - (60%)	Gaps:	23/348 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 KSKSLLKKHLTKEIFEKLKTKTTPSFNSTLLHCISSGMCN--HD--SGVGLYAPDPEAYKVFADL 110
            |..:.:..|||..::.:|..||||: ..||..||.:|:.|  |.  ..||:.|.|.|.|:|||:|
Mouse    59 KHNNCMASHLTPAVYARLCDKTTPT-GWTLDQCIQTGVDNPGHPFIKTVGMVAGDEETYEVFAEL 122

  Fly   111 FDPVIEEYH-----KCFKKTDKQPATAFGKGADFENLDPDGHFIVSTRVRCGRAVKGYPFNPCLT 170
            |||||:|.|     :..|.|....|:....|..      |..:::|:|||.||:::|....|..|
Mouse   123 FDPVIQERHNGYDPRTMKHTTDLDASKIRSGYF------DERYVLSSRVRTGRSIRGLSLPPACT 181

  Fly   171 EADYMELESKICGAVTSLTGEYKGKYMPLTGMDKCIQEQLIEDHYLF-KEGDRFLASAGASRYWP 234
            .|:..|:|..:..|::.|.|:..|:|..|:.|.:..|:|||:||:|| |.....|.:||.:|.||
Mouse   182 RAERREVERVVVDALSGLKGDLAGRYYRLSEMTEAEQQQLIDDHFLFDKPVSPLLTAAGMARDWP 246

  Fly   235 TGRGIFLNSAKNFLVWCNEEDHIRIISMEKGGDLGKVYDRMVGGVEALGKQLQ-----FNRDERL 294
            ..|||:.|:.|:||:|.|||||.|:|||||||::.:|::|...|::.:.|.:|     |..:|||
Mouse   247 DARGIWHNNEKSFLIWVNEEDHTRVISMEKGGNMKRVFERFCRGLKEVEKLIQERGWEFMWNERL 311

  Fly   295 GFLTFCPTNLGTSIRASVHIKLPNLMCDPDEMKKLADKYRLQIRGTSGEHSEAKGGVHDISNQRR 359
            |::..||:||||.:||.|||||| |:...:...|:.:..|||.|||.|..:.|.|.|.||||..|
Mouse   312 GYILTCPSNLGTGLRAGVHIKLP-LLSKDNRFPKILENLRLQKRGTGGVDTAATGSVFDISNLDR 375

  Fly   360 MGLTEYEIIKEMHDGIKGLIEAE 382
            :|.:|.|:::.:.||:..||:.|
Mouse   376 LGKSEVELVQLVIDGVNYLIDCE 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5144	NP_648284.1	arginine_kinase_like	40..382	CDD:153079	141/346 (41%)
Ckmt1	NP_001341998.1	Cardiolipin-binding. /evidence=ECO:0000250	40..64		1/4 (25%)
Ckmt1	NP_001341998.1	creatine_kinase_like	50..407	CDD:153076	142/348 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	197	1.000	Domainoid score	I3100
eggNOG	1	0.900	-	-		E1_COG3869
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	282	1.000	Inparanoid score	I2862
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58958
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000437
OrthoInspector	1	1.000	-	-		mtm8785
orthoMCL	1	0.900	-	-		OOG6_100675
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X315
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.730