Protein Alignment CG5144 and CKM

DIOPT Version :9

• Sequence 1: NP_648284.1
• Gene: CG5144 / 39040
• FlyBaseID: FBgn0035957
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001815.2
• Gene: CKM / 1158
• HGNCID: 1994
• Length: 381
• Species: Homo sapiens
• Alignment Length: 361
• Identity: 146/361 - (40%)
• Similarity: 216/361 - (59%)
• Gaps: 27/361 - (7%)

  Fly    40 EKGYKKLAESKSKSLLKKHLTKEIFEKLKTKTTPSFNSTLLHCISSGMCN--HD--SGVGLYAPD 100
            |:.|..|  ||..:.:.|.||.|:::||:.|.||| ..|:...|.:|:.|  |.  ..||..|.|
Human    17 EEEYPDL--SKHNNHMAKVLTLELYKKLRDKETPS-GFTVDDVIQTGVDNPGHPFIMTVGCVAGD 78

  Fly   101 PEAYKVFADLFDPVIEEYHKCFKKTDKQPATAFGKGADFENL----DPDGHFIVSTRVRCGRAVK 161
            .|:|:||.:||||:|.:.|..:|.|||...     ..:.|||    |.|.::::|:|||.||::|
Human    79 EESYEVFKELFDPIISDRHGGYKPTDKHKT-----DLNHENLKGGDDLDPNYVLSSRVRTGRSIK 138

  Fly   162 GYPFNPCLTEADYMELESKICGAVTSLTGEYKGKYMPLTGMDKCIQEQLIEDHYLF-KEGDRFLA 225
            ||...|..:..:...:|.....|:.|||||:||||.||..|.:..|:|||:||:|| |.....|.
Human   139 GYTLPPHCSRGERRAVEKLSVEALNSLTGEFKGKYYPLKSMTEKEQQQLIDDHFLFDKPVSPLLL 203

  Fly   226 SAGASRYWPTGRGIFLNSAKNFLVWCNEEDHIRIISMEKGGDLGKVYDRMVGGVEAL-------G 283
            ::|.:|.||..|||:.|..|:||||.|||||:|:|||||||::.:|:.|...|::.:       |
Human   204 ASGMARDWPDARGIWHNDNKSFLVWVNEEDHLRVISMEKGGNMKEVFRRFCVGLQKIEEIFKKAG 268

  Fly   284 KQLQFNRDERLGFLTFCPTNLGTSIRASVHIKLPNLMCDPDEMKKLADKYRLQIRGTSGEHSEAK 348
            ....:|  :.||::..||:||||.:|..||:||.:|...| :.:::..:.|||.|||.|..:.|.
Human   269 HPFMWN--QHLGYVLTCPSNLGTGLRGGVHVKLAHLSKHP-KFEEILTRLRLQKRGTGGVDTAAV 330

  Fly   349 GGVHDISNQRRMGLTEYEIIKEMHDGIKGLIEAECK 384
            |.|.|:||..|:|.:|.|.::.:.||:|.::|.|.|
Human   331 GSVFDVSNADRLGSSEVEQVQLVVDGVKLMVEMEKK 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5144	NP_648284.1	arginine_kinase_like	40..382	CDD:153079	144/357 (40%)
CKM	NP_001815.2	creatine_kinase_like	16..373	CDD:153076	146/361 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147543
Domainoid	1	1.000	196	1.000	Domainoid score	I3115
eggNOG	1	0.900	-	-		E1_COG3869
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	280	1.000	Inparanoid score	I2904
Isobase	1	0.950	-	0	Normalized mean entropy	S3995
OMA	1	1.010	-	-		QHG58958
OrthoDB	1	1.010	-	-		D287050at33208
OrthoFinder	1	1.000	-	-		FOG0000437
OrthoInspector	1	1.000	-	-		mtm8556
orthoMCL	1	0.900	-	-		OOG6_100675
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X315
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.620