Protein Alignment Doc1 and TBX4

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: XP_011523792.1
• Gene: TBX4 / 9496
• HGNCID: 11603
• Length: 609
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 146/407 - (35%)
• Similarity: 203/407 - (49%)
• Gaps: 84/407 - (20%)

  Fly    55 TLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRY 119
            |:..::..|...:||::||:.||||||||:|||||||.:|.::|:..:..|.:|:::||..|.||
Human   126 TIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIVPADDHRY 190

  Fly   120 KFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASMHKY 184
            ||..::|:.||.|||..|.|:|:|||||||||||..|.:.|.|:|||||.||..|||:|.|||||
Human   191 KFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKY 255

  Fly   185 QPRLHIIRSSELTQLPWAPQQAF---VFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQS- 245
            ||||||:::.|.... .:...||   |||||.|::||:|||.:||:|||:|||||||||.|..|
Human   256 QPRLHIVKADENNAF-GSKNTAFCTHVFPETSFISVTSYQNHKITQLKIENNPFAKGFRGSDDSD 319

  Fly   246 -RCKR---------------------KLNSSGN-------------------------------- 256
             |..|                     :|:::.:
Human   320 LRVARLQSKEYPVISKSIMRQRLISPQLSATPDVGPLLGTHQALQHYQHENGAHSQLAEPQDLPL 384

  Fly   257 STLESEDDGSSVSSCDSPQAKRQRQ-DFEQDSTGSVSPAYYGATHPVANPMSPYLRHHLSYGPSG 320
            ||..::.|.|....|...:|...|. |.....:...:|:..|..|...:| .||.:..||  ||.
Human   385 STFPTQRDSSLFYHCLKRRADGTRHLDLPCKRSYLEAPSSVGEDHYFRSP-PPYDQQMLS--PSY 446

  Fly   321 AAGLPPSIAAAYFGGVPPQI--------LPMPP------------ATYAPTVAPVSPVASQPVGS 365
            .:.:.|..|..| .|..|:|        ||.||            .:|:.......|....|...
Human   447 CSEVTPREACMY-SGSGPEIAGVSGVDDLPPPPLSCNMWTSVSPYTSYSVQTMETVPYQPFPTHF 510

  Fly   366 STPTTSPRPSTSTKRNS 382
            :..|..||..|.:.::|
Human   511 TATTMMPRLPTLSAQSS 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	105/189 (56%)
TBX4	XP_011523792.1	TBOX	129..318	CDD:238106	105/189 (56%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910