Protein Alignment Doc1 and TBX19

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_005140.1
• Gene: TBX19 / 9095
• HGNCID: 11596
• Length: 448
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 126/388 - (32%)
• Similarity: 183/388 - (47%)
• Gaps: 91/388 - (23%)

  Fly    54 PTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCR 118
            ||...::..||:..|||:|.::..|||:||:||||||.:::|::||:..|.|.:||:.||....|
Human    36 PTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVPTDSHR 100

  Fly   119 YKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASMHK 183
            :|:...:|||||..|..|...:|:|||||..||||....:.|:||||||. |:..|.|:|.|:||
Human   101 WKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIMLNSLHK 164

  Fly   184 YQPRLHIIRSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCK 248
            |:|::||:|.....::    .....||||:|:|||||||:.||.|||..|||||.|.::.:....
Human   165 YEPQVHIVRVGSAHRM----VTNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNHL 225

  Fly   249 RKLN--------------------------SSGNSTLE--------------------------- 260
            |.:.                          ::|||..:
Human   226 RDVPEAISESQHVTYSHLGGWIFSNPDGVCTAGNSNYQYAAPLPLPAPHTHHGCEHYSGLRGHRQ 290

  Fly   261 --------SEDDGSSVSSCDSPQAKRQRQDFE-QDSTGSVSPAYYGA------THPVANP-MSPY 309
                    ..:...||:..:|  :....|.|. .||..|:|...:.:      |:...|| .|||
Human   291 APYPSAYMHRNHSPSVNLIES--SSNNLQVFSGPDSWTSLSSTPHASILSVPHTNGPINPGPSPY 353

  Fly   310 -LRHHLSYGPSGAAGLPPSIAAAYFGGV---------PPQILPMPPATYAPTVAPVSPVASQP 362
             ....:|.|..|.:|..|.:.|:..|..         ||.:|    :|.|||.|.|. |..:|
Human   354 PCLWTISNGAGGPSGPGPEVHASTPGAFLLGNPAVTSPPSVL----STQAPTSAGVE-VLGEP 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	87/186 (47%)
TBX19	NP_005140.1	T-box	43..218	CDD:307177	87/179 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810