DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc1 and Tbx10

DIOPT Version :9

Sequence 1:	NP_648283.1	Gene:	Doc1 / 39039	FlyBaseID:	FBgn0028789	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_006230983.1	Gene:	Tbx10 / 688822	RGDID:	1584144	Length:	344	Species:	Rattus norvegicus

Alignment Length:	361	Identity:	134/361 - (37%)
Similarity:	190/361 - (52%)	Gaps:	89/361 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 PSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIG 115
            |..|.:..|..:||...||::|:::|||||:||:||||||:.:|.:.|::..|.|.:|::.:|:.
  Rat    16 PKNPRVSSVMVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPTFQVKIVGMDTLADYALLMDFIPLD 80

  Fly   116 DCRYK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVL 178
            |.||:  |..|.|:.||.|:|.:|.|::.||||||.||.|..|.:.|:|:|||||.:|.:|||:|
  Rat    81 DKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQWMRQIVSFDKLKLTNNLMDDNGHIIL 145

  Fly   179 ASMHKYQPRLHII------RSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAK 237
            .|||:||||.|::      .|:...|..:   ::|||.||:|.|||||||.|||:|||.:|||||
  Rat   146 NSMHRYQPRFHVVFVDPRKDSARYAQENF---KSFVFMETQFTAVTAYQNHRITQLKIASNPFAK 207

  Fly   238 GFRESGQ-----------SRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQDSTGSV 291
            ||||:..           |...|..:|.|...|:    ||         |:|     |:|::|:
  Rat   208 GFREADPDSWPATPRPLLSIPARSRSSLGPCLLK----GS---------AER-----EKDTSGT- 253

  Fly   292 SPAYYGATHPVANPMSPYLRHHLSYGPSGAAGLPPSIAAAYFGGVPPQILPMP-----PATYAP- 350
                     ..:.|.:|...||                         |:||.|     ||||.|
  Rat   254 ---------SASRPRTPTQTHH-------------------------QLLPAPDVLLAPATYRPL 284

  Fly   351 ---TVAPVSPVASQPVGSSTPTTS--PRPSTSTKRN 381
               .:.|.||   ...|:|....:  |.|:.||..|
  Rat   285 PYQNLYPGSP---SHAGTSRARLAPYPLPNISTAGN 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	97/205 (47%)
Tbx10	XP_006230983.1	T-box_TBX1_10-like	24..211	CDD:410313	95/189 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010