Protein Alignment Doc1 and tbx20

DIOPT Version :10

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_001030292.1
• Gene: tbx20 / 619590
• XenbaseID: XB-GENE-487334
• Length: 440
• Species: Xenopus tropicalis
• Alignment Length: 350
• Identity: 138/350 - (39%)
• Similarity: 192/350 - (54%)
• Gaps: 52/350 - (14%)

  Fly    49 MLPSRPTLPG-----VEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVL 108
            ::|:.|.:|.     :...||..:||.:||.:|||||||||||||||::|||.||::.:|.|.||
 Frog    79 LIPTTPVIPSEEMAKISCSLETKELWDKFHDLGTEMIITKSGRRMFPTIRVSFSGVDADAKYIVL 143

  Fly   109 LEMVPIGDCRYKFS--GSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLD 171
            :::||:.:.||:::  .|.|:.||.|:|..|.|:|:|||||.||.....|.:.|.|||||||.||
 Frog   144 MDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVHPDSPFTGEQLLKQMVSFEKVKLTNNELD 208

  Fly   172 SSGHIVLASMHKYQPRLHIIR----SSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDN 232
            ..|||:|.||||||||:|||:    ::.|..|.....:.|:|.||.|.|||||||..|||||||:
 Frog   209 QHGHIILNSMHKYQPRVHIIKKKDHTASLLNLKSEEFRTFIFQETVFTAVTAYQNQLITKLKIDS 273

  Fly   233 NPFAKGFRESGQ----------------SRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQ 281
            ||||||||:|.:                |..:..:.:.|:..:..| ||.::.|..|  |....:
 Frog   274 NPFAKGFRDSSRLTDIERESVESLIQKHSYARSPIRTYGDEDVLGE-DGQTMQSRGS--AFTTSE 335

  Fly   282 DFEQDSTGSVSPAYYGATHPVANPMSPYLRHHLSYGPSGAAGLPPSIAAAYFGGVPPQILPMPPA 346
            :....|..|.:..:.|..||          ..|:...:..|.|...|.....|.:||
 Frog   336 NLSLSSWVSSTSGFSGFQHP----------QSLTALGTSTASLATPIPHPIQGTLPP-------- 382

  Fly   347 TYAPTVAPVSP--VASQPVGSSTPT 369
             |:....|::|  :||...||. ||
 Frog   383 -YSRLGMPITPSALASSMQGSG-PT 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	T-box_Drosocross-like	59..241	CDD:410332	104/187 (56%)
tbx20	NP_001030292.1	T-box_TBX20-like	94..283	CDD:410319	105/188 (56%)
		T-box	98..282		104/183 (57%)
		P-loop containing Nucleoside Triphosphate Hydrolases	<314..>402	CDD:476819	23/109 (21%)