DRSC/TRiP Functional Genomics Resources

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Protein Alignment Doc1 and tbx1

DIOPT Version :9

Sequence 1:NP_648283.1 Gene:Doc1 / 39039 FlyBaseID:FBgn0028789 Length:391 Species:Drosophila melanogaster
Sequence 2:NP_001030290.1 Gene:tbx1 / 619587 XenbaseID:XB-GENE-478084 Length:463 Species:Xenopus tropicalis


Alignment Length:365 Identity:131/365 - (35%)
Similarity:192/365 - (52%) Gaps:82/365 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly    54 PTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCR 118
            |.:..:..:||...||.:|:::|||||:||:||||||:.:|.:.|::..|.|.:|::.||:.|.|
 Frog   105 PKVANITVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKIFGMDPMADYMLLMDFVPVDDKR 169

  Fly   119 YK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASM 181
            |:  |..|.|:.||.|:|.:|.|::.||||||.||.|..|.:.|:|:|||||.||.:|||:|.||
 Frog   170 YRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILNSM 234

  Fly   182 HKYQPRLHII-----RSSELTQLPWAPQ--QAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGF 239
            |:||||.|::     :.||    .:|.:  :.|||.||.|.|||||||.|||:|||.:|||||||
 Frog   235 HRYQPRFHVVYVDPRKDSE----KYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 295

  Fly   240 RE------------------SGQSRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQD 286
            |:                  :..:|.:..::|...:..:.:.||              |:::|:|
 Frog   296 RDCDPEDWPRNHRPGSLPLMNAFARSRNPVSSPPQNGSDKDGDG--------------RREYERD 346

  Fly   287 STGSVSPAYYGATHP-----VANPMSPYLRHHLSYGPSGAAGLP---PSIAAAYFGGVPPQILPM 343
            ::|  :|.:..|.|.     |.:|..|.        |.|...|.   ||         ||..|.:
 Frog   347 TSG--TPLHGDAAHQQLMSRVLSPSLPV--------PGGLVPLSTGRPS---------PPHELRL 392

  Fly   344 PPAT-------YAPTVAPVSPVASQPVGSST-PTTSPRPS 375
            .|.:       :.|...|.|  ....:|:.| |...|.||
 Frog   393 DPHSQGSEPLHHHPYKYPTS--YDHYLGAKTRPAPYPLPS 430

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Doc1NP_648283.1 TBOX 58..245 CDD:238106 98/213 (46%)
tbx1NP_001030290.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 39..58
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 75..103
T-box 112..297 CDD:366363 97/188 (52%)
T-box 114..297 97/186 (52%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 320..354 9/49 (18%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 367..405 11/54 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11267
Phylome 00.000 Not matched by this tool.
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2837
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.130

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