Protein Alignment Doc1 and tbx18

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_705951.1
• Gene: tbx18 / 572713
• ZFINID: ZDB-GENE-020529-2
• Length: 554
• Species: Danio rerio
• Alignment Length: 420
• Identity: 154/420 - (36%)
• Similarity: 208/420 - (49%)
• Gaps: 89/420 - (21%)

  Fly    30 PDPFPSMLPFNMPHQQPHMMLPSRPTLPGVEAK--LENNDLWQQFHKIGTEMIITKSGRRMFPSM 92
            |:|...:|....|..|...:|....|..|.|.:  |:.:|||::||:|||||||||:||||||:|
Zfish    78 PEPEDVLLDSPQPASQGAQVLVQSATSSGEEMRVDLQGSDLWKRFHEIGTEMIITKAGRRMFPAM 142

  Fly    93 RVSLSGLEEEASYCVLLEMVPIGDCRYK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQS 155
            ||.::||:....|.:.:::||:.:.||:  :..|:|:.||.|:...|.|:|:||||||:|..|..
Zfish   143 RVKIAGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMR 207

  Fly   156 QALLFNKVKLTNNTLDSSGHIVLASMHKYQPRLHIIR---SSELTQLPWAPQ----QAFVFPETE 213
            |.:.|:|:|||||.||..|||:|.||||||||:|:||   ..||:.:...|.    :||.|.||.
Zfish   208 QVISFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKECGEELSPVKAVPTGDGVKAFSFTETV 272

  Fly   214 FVAVTAYQNDRITKLKIDNNPFAKGFRESGQSRCKRKLNSSGNS---------TLESED------ 263
            |..||||||.:||:||||.||||||||:||::|  ..|.:...|         ||..||
Zfish   273 FTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNR--MGLEALVESYAFWRPSLRTLTFEDILGITK 335

  Fly   264 ---------DGSSV-----SSCDSPQAKRQRQDFEQDSTGSVSPAYYGATHPVANPMSPYLRHHL 314
                     .|||.     |||.||       .|...| |:.....|......::|:     |.
Zfish   336 QGAAGSHGVVGSSAHLLSSSSCPSP-------TFHLGS-GAGPVCDYSTCSRTSHPL-----HR- 386

  Fly   315 SYGPSGAA------------GLPPSIAAAYFG------------GVPPQILPMPPATYAPTVAPV 355
             ||||.:|            ....|.::.|..            |:|.||..||..|
Zfish   387 -YGPSLSADSYSRLTSPTADAFSTSRSSTYVSGTESEAFSCTQTGLPIQIHSMPSTT-------- 442

  Fly   356 SPVASQPVGSSTPTTSPRPSTSTKRNSFSI 385
            |.:.....|.:....|...||....|.|.:
Zfish   443 SQLQYLMPGHAHNAFSTNQSTQGSYNGFRL 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	105/197 (53%)
tbx18	NP_705951.1	TBOX	109..304	CDD:238106	103/194 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.040