Protein Alignment Doc1 and tbx3a

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_001095140.2
• Gene: tbx3a / 556870
• ZFINID: ZDB-GENE-070209-80
• Length: 689
• Species: Danio rerio
• Alignment Length: 596
• Identity: 177/596 - (29%)
• Similarity: 244/596 - (40%)
• Gaps: 235/596 - (39%)

  Fly    25 IMQRIPDPFPSMLPF-NMPHQQPHMMLPSRPTLPGVEAK------LENNDLWQQFHKIGTEMIIT 82
            ||:::.....:.|.| ::.||..|:. |.:...|..|.:      ||..:||:.|||.||||:||
Zfish    58 IMEQLMGAAETGLHFSSLGHQAAHLR-PLKTLEPEEEVEDDPKVHLEAKELWELFHKRGTEMVIT 121

  Fly    83 KSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSP 147
            ||||||||..:|..:||:::|.|.:|:::|...||||||..|:|:.||.|:|:.|:|||:|||||
Zfish   122 KSGRRMFPPFKVRCTGLDKKAKYILLMDIVAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSP 186

  Fly   148 ATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASMHKYQPRLHIIRSSELTQLPWAPQQAFVFPET 212
            |||..|.|:.:.|:|:|||||..|..|..:|.||||||||.||:|::::.:||::..:.:|||||
Zfish   187 ATGEQWMSKVVNFHKLKLTNNISDKHGFTILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPET 251

  Fly   213 EFVAVTAYQNDRITKLKIDNNPFAKGFRESGQSR------------------------------- 246
            :|:||||||||:||:||||:||||||||::|..|
Zfish   252 DFIAVTAYQNDKITQLKIDHNPFAKGFRDTGNGRREKRKQLALQSMRSYEEQQKKENGTSDDSSG 316

  Fly   247 ------CKRKLNSSGNSTL---------------ESED---------DGSSVSS----------- 270
                  |.|:.:|...||.               :.||         |.|.:|:
Zfish   317 EQASFKCFRQASSPAVSTAGHNHLKDFCDSDEDSDEEDKDANAKEGPDSSKISTTTEDSKDQDAG 381

  Fly   271 --------CDSPQAKRQ---RQDFEQ--------------------------DSTGSVSPAYY-- 296
                    .||...:|.   |.|...                          |...:||...|
Zfish   382 LGKSVFGESDSSSGRRSEKTRADSRSPITLISSTTRSGEELKSPVREPAKTTDDCRTVSKENYMP 446

  Fly   297 ------GATHPVANPM---------------------SPYLRHHLSYGPSG-----AAGLPPSIA 329
                  ||.|...|.:                     .|:|.|...:...|     |||:.|.:|
Zfish   447 LTVQTDGAAHLNQNHLHNFGFPPGLAGQQFFNHLGGAHPFLLHPSQFNMGGAFSNMAAGMGPILA 511

  Fly   330 AAYFGGV----------PPQIL---PMP------------------------PATYAPTVAPVSP 357
            |...|||          |.|.|   |||                        |.||....|..|.
Zfish   512 AVSSGGVGSLDGSSLPSPSQSLTGAPMPFHLQQHVLASQGLAMSPFGGLFPYPYTYMAAAAAASS 576

  Fly   358 VAS------------------------------------QPVGSS-----------TPTTSPRPS 375
            .||                                    ||:.||           :|.::...|
Zfish   577 AASSSVHRHPFLSAVRPRLRYSPYSLPSVPDSTLLTTAMQPMASSGLEVKGDGMNTSPASAALDS 641

  Fly   376 TSTKRNSFSIS 386
            ..|.|:|.|:|
Zfish   642 EVTSRSSGSVS 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	107/192 (56%)
tbx3a	NP_001095140.2	TBOX	99..282	CDD:238106	105/182 (58%)
		TBX	298..385	CDD:204975	10/86 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.840