DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc1 and Mga

DIOPT Version :9

Sequence 1:	NP_648283.1	Gene:	Doc1 / 39039	FlyBaseID:	FBgn0028789	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_006234859.1	Gene:	Mga / 499874	RGDID:	1561597	Length:	3093	Species:	Rattus norvegicus

Alignment Length:	295	Identity:	122/295 - (41%)
Similarity:	173/295 - (58%)	Gaps:	37/295 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPI 114
            ||:..|:..:...|:||.:|.:||...||||:||.||||||..|..::||:....|.:::::.|:
  Rat    66 LPADCTVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPV 130

  Fly   115 GDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLA 179
            ...|||::|..|.|:|.|||....|:::||:||:||.:|..|.:.|.|:||||||||..|||:|.
  Rat   131 DSHRYKWNGRWWEPSGKAEPHILGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILH 195

  Fly   180 SMHKYQPRLHII---RSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRE 241
            |||:|.||||::   :::|:.||.......|.||:|||.|||||||.:||:||||.||||||||:
  Rat   196 SMHRYLPRLHLVPAEKATEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRD 260

  Fly   242 SGQS----RCKRKLNSS---GNSTLES--------EDDGSSVSSCDSPQAKRQRQ---------- 281
            .|.|    |..::.|||   |||...|        |.:||.:.|.|.....|..:
  Rat   261 DGLSSKPQRDGKQRNSSDQEGNSVSSSPGHRVRLTEGEGSEIHSGDFDPVLRGHETSSLGLEKAP 325

  Fly   282 -DFEQDSTGSVSPAYYGATHPVANPMSPYLRHHLS 315
             :.:||..|.::.   .:||.|     |.|:..:|
  Rat   326 NNVKQDFLGFMNT---DSTHEV-----PQLKREIS 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	95/189 (50%)
Mga	XP_006234859.1	T-box_MGA-like	75..260	CDD:410321	93/184 (51%)
		DUF4801	1040..1081	CDD:406462
		Herpes_BLLF1	<1519..1828	CDD:282904
		Atrophin-1	1692..>2024	CDD:397323
		bHLHzip_MGA	2454..2518	CDD:381481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910