Protein Alignment Doc1 and Tbx3

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_853669.1
• Gene: Tbx3 / 353305
• RGDID: 735203
• Length: 743
• Species: Rattus norvegicus
• Alignment Length: 494
• Identity: 160/494 - (32%)
• Similarity: 222/494 - (44%)
• Gaps: 157/494 - (31%)

  Fly    25 IMQRIPDPFPSMLPFNMPHQQPHM-----MLPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKS 84
            ||.::.....:.:||:....|.|:     |.|........:..||..:||.||||.||||:||||
  Rat    64 IMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKS 128

  Fly    85 GRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPAT 149
            ||||||..:|..|||:::|.|.:|::::...||||||..|:|:.||.|:|:.|:|||:|||||||
  Rat   129 GRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPAT 193

  Fly   150 GAHWQSQALLFNKVKLTNNTLDSSG--------------------HIVLASMHKYQPRLHIIRSS 194
            |..|.|:.:.|:|:|||||..|..|                    ..:|.||||||||.||:|::
  Rat   194 GEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRAN 258

  Fly   195 ELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQSRC-KRK-------- 250
            ::.:||::..:.::||||||:||||||||:||:|||||||||||||::|..|. |||
  Rat   259 DILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMR 323

  Fly   251 ---------------------------------LNSSGNSTL------ESEDDGSSVS------- 269
                                             :::.|.|.|      |:|.|..:.|
  Rat   324 VFDERHKKETGTSDESSSEQAAFNCFAQASSPAVSTVGTSNLKDLCPSEAESDAEAESKEEHGPE 388

  Fly   270 SCDSPQAKRQRQDFEQDSTGSVSPAYYGATHPVANP-----------MSPYLRH----------- 312
            :||:  ||......|:......|||......| |.|           .||..||
  Rat   389 ACDT--AKISTTTAEEPGRDKGSPATRAQLFP-AEPSRARDTARLDKASPDSRHSPATISSSTRV 450

  Fly   313 ------------------------------------------HLSYGPSGAAGLPPSIAA-AYFG 334
                                                      ||:.||....|..|.:|. .:|.
  Rat   451 PGADEHRSPGREGPVSAKVDEARALPAKDAFAPLSVQTDATAHLTQGPLPGLGFAPGLAGQQFFN 515

  Fly   335 GVPPQILPMPPATYA------PTVAPVSPVASQPVGSST 367
            |.|   |.:.|..:|      ...|.:.|:.:...|:||
  Rat   516 GHP---LFLHPGQFAMGGAFSSMAAGMGPLLATVSGAST 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	108/206 (52%)
Tbx3	NP_853669.1	T-box_TBX2_3-like	101..305	CDD:410314	106/203 (52%)
		TBX	323..404	CDD:403708	12/82 (15%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	371..467		19/98 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810