DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc1 and Mga

DIOPT Version :9

Sequence 1:	NP_648283.1	Gene:	Doc1 / 39039	FlyBaseID:	FBgn0028789	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	XP_006499750.1	Gene:	Mga / 29808	MGIID:	1352483	Length:	3091	Species:	Mus musculus

Alignment Length:	295	Identity:	117/295 - (39%)
Similarity:	170/295 - (57%)	Gaps:	37/295 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPI 114
            ||:..|:..:...|:||.:|.:||...||||:||.||||||..|..::||:....|.:::::.|:
Mouse    66 LPADCTVGKITVTLDNNSMWNEFHNRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILVMDISPV 130

  Fly   115 GDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLA 179
            ...|||::|..|.|:|.|||....|:::||:||:||.:|..|.:.|.|:||||||||..|||:|.
Mouse   131 DSHRYKWNGRWWEPSGKAEPHILGRVFIHPESPSTGHYWMHQPVSFYKLKLTNNTLDQEGHIILH 195

  Fly   180 SMHKYQPRLHII---RSSELTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRE 241
            |||:|.||||::   :::|:.||.......|.||:|||.|||||||.:||:||||.||||||||:
Mouse   196 SMHRYLPRLHLVPAEKATEVIQLNGPGVHTFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRD 260

  Fly   242 SGQSRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQDSTGSVSPAYYG--------- 297
            .|.|...::.....||   |:.:|:||||..:.:.:....:..:..:|...|...|
Mouse   261 DGLSSKPQREGKQRNS---SDQEGNSVSSSPAHRVRLTEGEGSEIHSGDFDPVLRGHEASSLSLE 322

  Fly   298 -----------------ATHPVANPMSPYLRHHLS 315
                             :||.|     |.|:|.:|
Mouse   323 KAPHNVKQDFLGFMNTDSTHEV-----PQLKHEIS 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	95/189 (50%)
Mga	XP_006499750.1	TBOX	74..264	CDD:238106	95/189 (50%)
		DUF4801	1038..1080	CDD:374336
		DUF5585	<1510..>1811	CDD:375359
		Atrophin-1	1729..>2023	CDD:367360
		bHLHzip_MGA	2452..2516	CDD:381481
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910