DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc1 and Tbx15

DIOPT Version :9

Sequence 1:	NP_648283.1	Gene:	Doc1 / 39039	FlyBaseID:	FBgn0028789	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001382004.1	Gene:	Tbx15 / 295315	RGDID:	1308094	Length:	602	Species:	Rattus norvegicus

Alignment Length:	388	Identity:	140/388 - (36%)
Similarity:	200/388 - (51%)	Gaps:	85/388 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 VEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEMVPIGDCRYK--F 121
            ::.:|:..|||::||.|||||||||:||||||:|||.::||:....|.:.:::||:.:.||:  :
  Rat   113 IQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVY 177

  Fly   122 SGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSSGHIVLASMHKYQP 186
            ..|:|:.||.|:...|.|:|:||||.|:|..|..|.:.|:|:|||||.||..|||:|.|||||||
  Rat   178 HSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQP 242

  Fly   187 RLHIIR---SSELTQLPWAP----QQAFVFPETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQ 244
            |:|:||   ||:|:.....|    .:.|.||||.|..||||||.:||:||||.||||||||:||:
  Rat   243 RVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGR 307

  Fly   245 SRC---------------KRKLNSSGNSTLESEDDGSSVSSCDSPQAKRQRQDFEQDSTGSVSPA 294
            :|.               .|.|.....:|::.:..||:.:|..:            .|||:.||:
  Rat   308 NRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPST------------SSTGTPSPS 360

  Fly   295 YYGATHPVANPMSPYLRH------------------HLS-YGP-----------------SGAAG 323
              .::|.::...||...|                  :|| |.|                 ||...
  Rat   361 --ASSHLLSPSCSPPTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNR 423

  Fly   324 LPPSIAAAYFGGVPPQILPMPPATYAPTVAPVSPVASQPVGSSTPTTSPRPSTSTKRNSFSIS 386
            |....|:|          ..|..|:.|...| |.::..|...|.|:.|...:...:..||..|
  Rat   424 LQSGTASA----------TQPSETFMPQRTP-SLISGIPTPPSLPSNSKMEAYGGQLGSFPTS 475

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	103/194 (53%)
Tbx15	NP_001382004.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910