DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc1 and tbx15

DIOPT Version :9

Sequence 1:	NP_648283.1	Gene:	Doc1 / 39039	FlyBaseID:	FBgn0028789	Length:	391	Species:	Drosophila melanogaster
Sequence 2:	NP_001315362.1	Gene:	tbx15 / 246222	ZFINID:	ZDB-GENE-020529-1	Length:	616	Species:	Danio rerio

Alignment Length:	306	Identity:	126/306 - (41%)
Similarity:	176/306 - (57%)	Gaps:	56/306 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 DPFPSMLPFNMPHQQPHMMLPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVS 95
            ||.||                  .::..::.:|:..|||::||.|||||||||:||||||:|||.
Zfish   100 DPSPS------------------ASMEEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVK 146

  Fly    96 LSGLEEEASYCVLLEMVPIGDCRYK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQAL 158
            :.||:....|.:.:::||:.:.||:  :..|:|:.||.|:...|.|:|:||||.|:|..|..|.:
Zfish   147 IVGLDPHQQYYIAMDIVPVDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVV 211

  Fly   159 LFNKVKLTNNTLDSSGHIVLASMHKYQPRLHIIR---SSELTQLPWAPQ----QAFVFPETEFVA 216
            .|:|:|||||.||..|||:|.||||||||:|:||   ||||:.....|.    :.|.||||.|..
Zfish   212 SFDKLKLTNNELDDQGHIILHSMHKYQPRVHVIRKDFSSELSPTKPVPTGEGVKTFSFPETVFTT 276

  Fly   217 VTAYQNDRITKLKIDNNPFAKGFRESGQSRC---------------KRKLNSSGNSTLESEDDGS 266
            ||||||.:||:||||.||||||||:||::|.               .|.|.....:.::.:..||
Zfish   277 VTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLTFEDFTNMQKQQGGS 341

  Fly   267 SVSSCDSPQAKRQRQDFEQDSTGSVSPAYYGATHPVANPMSPYLRH 312
            :.:|..:            .|||:.||:  ||||.::...||...|
Zfish   342 TGTSPTT------------SSTGTPSPS--GATHLLSPSCSPPTFH 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	104/195 (53%)
tbx15	NP_001315362.1	TBOX	110..305	CDD:238106	104/194 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2837
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.040