Protein Alignment Doc1 and Tbx5

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: XP_006530342.1
• Gene: Tbx5 / 21388
• MGIID: 102541
• Length: 537
• Species: Mus musculus
• Alignment Length: 386
• Identity: 144/386 - (37%)
• Similarity: 199/386 - (51%)
• Gaps: 76/386 - (19%)

  Fly    51 PSRPT-------LPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVL 108
            ||.|.       :.|::..|...:||.:||::||||||||:|||||||.:|.::||..:..|.:|
Mouse    58 PSSPQAAFTQQGMEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILL 122

  Fly   109 LEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNNTLDSS 173
            :::||..|.||||:.::|...|.|||..|.|:|:|||||||||||..|.:.|.|:|||||.||..
Mouse   123 MDIVPADDHRYKFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPF 187

  Fly   174 GHIVLASMHKYQPRLHIIRSSELTQLPWAPQQAF---VFPETEFVAVTAYQNDRITKLKIDNNPF 235
            |||:|.|||||||||||:::.|.... .:...||   |||||.|:|||:|||.:||:|||:||||
Mouse   188 GHIILNSMHKYQPRLHIVKADENNGF-GSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPF 251

  Fly   236 AKGFRESG-------------------QSRCKRKLNSSGNSTLESEDDGSSVSS-------CDS- 273
            |||||.|.                   :|..:.|: :|.:|...||....|.||       |::
Mouse   252 AKGFRGSDDLELHRMSRMQSKEYPVVPRSTVRHKV-TSNHSPFSSETRALSTSSNLGSQYQCENG 315

  Fly   274 ---------------PQAKR--------QRQDFEQDSTG--------SVSPA----YYGATHPVA 303
                           |.|:.        :|:|.|..||.        ..||:    :|.:.:|..
Mouse   316 VSGPSQDLLPPPNPYPLAQEHSQIYHCTKRKDEECSSTEHPYKKPYMETSPSEEDTFYRSGYPQQ 380

  Fly   304 NPMSPYLRHHLSYGPS--GAAGLPPSIAAAYFGGVPPQILPMPPATYAPTVAPVSPVASQP 362
            ..:|...|...:...:  .|:..|||........:.....|..|:..:.||..|.|:...|
Mouse   381 QGLSTSYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLP 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	107/208 (51%)
Tbx5	XP_006530342.1	TBOX	72..260	CDD:238106	107/188 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910