Protein Alignment Doc1 and Eomes

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_034266.2
• Gene: Eomes / 13813
• MGIID: 1201683
• Length: 707
• Species: Mus musculus
• Alignment Length: 439
• Identity: 139/439 - (31%)
• Similarity: 192/439 - (43%)
• Gaps: 135/439 - (30%)

  Fly    47 HMMLPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRMFPSMRVSLSGLEEEASYCVLLEM 111
            |:.|.:||             ||.:||:..|||||||.||||||.:..:::||...|.|.|.:|:
Mouse   270 HVYLCNRP-------------LWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEV 321

  Fly   112 VPIGDCRYKFSGSQWVPAGGAE-PQSPQRMYLHPDSPATGAHWQSQALLFNKVKLTNN---TLDS 172
            |......::|.|.:||..|.|: .....:||:||:||.||:||..|.:.|.|:|||||   ..::
Mouse   322 VLADPNHWRFQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNNKGANNNN 386

  Fly   173 SGHIVLASMHKYQPRLHIIRSSE-----LTQLPWAPQQAFVFPETEFVAVTAYQNDRITKLKIDN 232
            :..|||.|:|||||||||:..:|     |.: | :..|.|.|.||:|:|||||||..||:||||:
Mouse   387 TQMIVLQSLHKYQPRLHIVEVTEDGVEDLNE-P-SKTQTFTFSETQFIAVTAYQNTDITQLKIDH 449

  Fly   233 NPFAKGFRESGQSRCKRKLNSSGNSTLESEDDGSSVSSCDSPQAKR------------------- 278
            ||||||||::..|           ....||:|..:.|..|||::.:
Mouse   450 NPFAKGFRDNYDS-----------MYTASENDRLTPSPTDSPRSHQIVPGGRYGVQNFFPEPFVN 503

  Fly   279 ---QRQDFEQDST-----GSVSPAYYGATHPVANPMSPYL--------RHHLSYG---------- 317
               |.:.:..:.|     |.:||.   .:..||||...:|        .:.|..|
Mouse   504 TLPQARYYNGERTVPQTNGLLSPQ---QSEEVANPPQRWLVTPVQQPVTNKLDIGSYESEYTSST 565

  Fly   318 --PSGAAGLP--PSIAAAYFGGVPPQILP------------------MP-PATYAPTVAPVSPVA 359
              |.|...||  .|.|..|:   |....|                  :| .:..:|.|.|...:|
Mouse   566 LLPYGIKSLPLQTSHALGYY---PDPTFPAMAGWGGRGAYQRKMAAGLPWTSRMSPPVFPEDQLA 627

  Fly   360 SQPV----GSSTPTTSP----------------------RPSTSTKRNS 382
            .:.|    .||...|.|                      .|||.:..||
Mouse   628 KEKVKEEISSSWIETPPSIKSLDSSDSGVYNSACKRKRLSPSTPSNGNS 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	91/195 (47%)
Eomes	NP_034266.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	27..125
		TBOX	269..462	CDD:238106	95/206 (46%)
		T-box_assoc	484..705	CDD:292794	36/199 (18%)
		Required for transcription activation. /evidence=ECO:0000250	592..707		15/85 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	642..689		7/35 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910