Protein Alignment Doc1 and Tbx10

DIOPT Version :9

• Sequence 1: NP_648283.1
• Gene: Doc1 / 39039
• FlyBaseID: FBgn0028789
• Length: 391
• Species: Drosophila melanogaster
• Sequence 2: NP_001001320.1
• Gene: Tbx10 / 109575
• MGIID: 1261436
• Length: 385
• Species: Mus musculus
• Alignment Length: 387
• Identity: 137/387 - (35%)
• Similarity: 199/387 - (51%)
• Gaps: 77/387 - (19%)

  Fly    28 RIPDPFPS----MLPFNMPHQQPHMMLPSRPTLPGVEAKLENNDLWQQFHKIGTEMIITKSGRRM 88
            |:...|||    |........:|....|..|.:..|..:||...||::|:::|||||:||:||||
Mouse    30 RLGTRFPSGSCTMSTEAQAMAEPTGQGPKNPRVSSVMVQLEMKPLWEEFNQLGTEMIVTKAGRRM 94

  Fly    89 FPSMRVSLSGLEEEASYCVLLEMVPIGDCRYK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGA 151
            ||:.:|.:.|::..|.|.:|::.:|:.|.||:  |..|.|:.||.|:|.:|.|::.||||||.||
Mouse    95 FPTFQVKILGMDTLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGA 159

  Fly   152 HWQSQALLFNKVKLTNNTLDSSGHIVLASMHKYQPRLHII------RSSELTQLPWAPQQAFVFP 210
            .|..|.:.|:|:|||||.:|.:|||:|.|||:||||.|::      .|:...|..:   ::|||.
Mouse   160 QWMRQIVSFDKLKLTNNLMDDNGHIILNSMHRYQPRFHVVFVDPRKDSARYAQENF---KSFVFT 221

  Fly   211 ETEFVAVTAYQNDRITKLKIDNNPFAKGFRESGQSRC----KRKLNSSGNSTLESEDDGSSVSSC 271
            ||:|.|||||||.|||:|||.:|||||||||:.....    :..|:....|.       ||:|.|
Mouse   222 ETQFTAVTAYQNHRITQLKIASNPFAKGFREADPDSWPVTPRPLLSIPARSR-------SSLSPC 279

  Fly   272 -DSPQAKRQRQDFEQDSTGSVSPAYYGATHPVANPMSPYLRHHLSYGPSGAAGLPPSIAAAYFGG 335
             ....|:|::...:..::.|.:|     |.|          |:
Mouse   280 LLKGSAEREKDTSKASASSSRTP-----TQP----------HN---------------------- 307

  Fly   336 VPPQILPMP-----PATYAP----TVAPVSPV-ASQPVGSSTPTTSPRPSTSTKRNSFSISA 387
               |:||.|     ||||.|    .:.|.||. |..|.....|...|..||:..:...:::|
Mouse   308 ---QLLPAPDVLLAPATYRPLPYQNLYPGSPSRAGPPRARLAPYPLPNISTAGDQEDPTLAA 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc1	NP_648283.1	TBOX	58..245	CDD:238106	97/194 (50%)
Tbx10	NP_001001320.1	TBOX	67..254	CDD:238106	96/189 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	283..310		8/66 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..359		9/30 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910