Protein Alignment Doc2 and Tbx19

DIOPT Version :10

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_114394.1
• Gene: Tbx19 / 83993
• MGIID: 1891158
• Length: 446
• Species: Mus musculus
• Alignment Length: 432
• Identity: 134/432 - (31%)
• Similarity: 201/432 - (46%)
• Gaps: 88/432 - (20%)

  Fly    56 VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSG 120
            :::.|::..||::|.::..|||:||:||||||.:::||:||:..:.|.:||:.|.....|:|:..
Mouse    39 LQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLLDFVRTDSHRWKYVN 103

  Fly   121 SQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQPRL 185
            .:|||||..|..|...:|:|||||..||||...||.|:||||||. |:..|.|:|.|:|||:|::
Mouse   104 GEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNK-LNGGGQIMLNSLHKYEPQV 167

  Fly   186 HVIRTADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMSS 250
            |::|.....::    .....|.||:|:|||||||:.||.|||..|||||.|.:..:   :..:..
Mouse   168 HIVRVGGAHRM----VMNCSFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKE---RNHLKD 225

  Fly   251 SPTGEDQDQSPSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRSNGSACSLSSSLD 315
            .|....:.|..:.||                  .||. .:.:.||           .|:.::|..
Mouse   226 VPEAISESQHVTYSH------------------LGGW-ILSNPDG-----------VCTAANSNY 260

  Fly   316 DQSVPGASSLALGSPPPHLH----------SHSH-PHPL----QARSASSVFMQHFQQNMQSLLR 365
            ..:.|      |..|.||.|          .|.. |:|.    :..|.|...::....|:|....
Mouse   261 QYATP------LPLPAPHTHHGCEHYAGLRGHRQAPYPSAYMHRNHSPSVNLIESSSNNLQVFSG 319

  Fly   366 P-SLVDLACT----YFGRPHEYGGAIQASPMYPPAAMLQAGLGPHPGL------NLPPGVSGADL 419
            | |...|:.|    ....||..|      |:.|       |..|:|.|      ...|..||:::
Mouse   320 PDSWTSLSSTPHASILSVPHSNG------PINP-------GPSPYPCLWTISNGGGGPVASGSEV 371

  Fly   420 ISDESGAEELELDVGSETSTL--EQSTQEQPLE---QPSTRS 456
            .:..||...|.....:..|:|  .|:|....:|   :||..|
Mouse   372 HASTSGTILLGNPAVTSPSSLLPTQATTSAGVEVLGEPSLTS 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	T-box_Drosocross-like	56..238	CDD:410332	84/181 (46%)
Tbx19	NP_114394.1	T-box_TBX19-like	34..216	CDD:410327	84/181 (46%)