Protein Alignment Doc2 and tbx21

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001164070.1
• Gene: tbx21 / 797797
• ZFINID: ZDB-GENE-080104-3
• Length: 609
• Species: Danio rerio
• Alignment Length: 473
• Identity: 154/473 - (32%)
• Similarity: 219/473 - (46%)
• Gaps: 96/473 - (20%)

  Fly    49 PRVTLPGVEMT------LQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLE 107
            |..:|||::::      |.|..||.:||:..|||||||.||||||.:..:::.|:..::|.:.::
Zfish   138 PMYSLPGLQVSGKTQVLLNNYPLWAKFHKYQTEMIITKQGRRMFPFLSFNITSLDPSAHYNIYVD 202

  Fly   108 MVPIGDCRYKFSGSQWVPAGGAEPQSP-QRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSG 171
            :|......:::.|.:||..|.||...| .|||:|||||.||.||..|.:.|.|:|||||...::.
Zfish   203 VVLADQHHWRYQGGKWVQCGKAEGNMPGNRMYMHPDSPNTGTHWMRQEVSFGKLKLTNNKGSSNN 267

  Fly   172 ---HIVLASMHKYQPRLHVIRT-ADLAQIPW--APQQAFVFAETEFVAVTAYQNDRITKLKIDNN 230
               .|||.|:||||||||::.. .|..:.|:  :..|.|||.||:|:|||||||..||:||||:|
Zfish   268 VAQMIVLQSLHKYQPRLHIVEVKEDGTEDPFLTSKTQTFVFPETQFIAVTAYQNADITQLKIDHN 332

  Fly   231 PFAKGFRETGQSRC----KRKMSSSPTGEDQDQSPS-LSHSQSQSESDMSPTKGGGETAGGTSSI 290
            |||||||:...:..    ..:::.|||...|..|.| ..|....|:..|||.
Zfish   333 PFAKGFRDNYDTLYAPPDPDRLTPSPTESQQLLSGSCYPHQPYLSDQYMSPL------------- 384

  Fly   291 GDSDGPQIK----------------RLRSNGSACSLSSSLDDQSVP-----------GASSLALG 328
                 ||.:                ...|..|...|||   .|:||           ..:|.:|.
Zfish   385 -----PQSRFYSREPVSMTQPCPKDPTSSPHSRWYLSS---QQAVPPNRLDFSAYETEYTSNSLY 441

  Fly   329 SPPPHLHSHSHPHPLQARSASSVFMQHFQQNMQSLLRPSLVDLACTYFGRPHEYGGAIQASPMY- 392
            .|.| |.|..| |||...|.:.     |.....|...|.    |.|..|||         ||.|
Zfish   442 KPFP-LQSSPH-HPLSYYSENP-----FTSGAVSSANPG----AWTASGRP---------SPQYL 486

  Fly   393 -------PPAAMLQAGLGPHPGLNLPPGVSGADLISDESGAEELELDVGSETSTLEQSTQEQPLE 450
                   |.:::......|.|..:..|..:.:...:..|..|.....:..:.|  ::||::..:|
Zfish   487 NHPHHSKPTSSLSWFRAVPSPAASSSPTATNSRFHASPSLLEPQRQPLLQDKS--KESTEDTWIE 549

  Fly   451 QPSTRSKGFSISAILGGG 468
            .||.:|...:.|.:..||
Zfish   550 APSVKSVDSADSGLFEGG 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	92/199 (46%)
tbx21	NP_001164070.1	TBOX	150..343	CDD:238106	91/192 (47%)
		T-box_assoc	363..608	CDD:292794	56/248 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910