Protein Alignment Doc2 and tbr1

DIOPT Version :10

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001072587.1
• Gene: tbr1 / 780042
• XenbaseID: XB-GENE-942241
• Length: 677
• Species: Xenopus tropicalis
• Alignment Length: 476
• Identity: 153/476 - (32%)
• Similarity: 220/476 - (46%)
• Gaps: 108/476 - (22%)

  Fly    52 TLPGV-----EMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPI 111
            |.||:     ::.|.|..||.:||:..|||||||.||||||.:..::|||:..::|.:.::::..
 Frog   197 TQPGLVPGKAQVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILA 261

  Fly   112 GDCRYKFSGSQWVPAGGAEPQ-SPQRMYLHPDSPATGAHWQAQPILFNKVKLTNN--TLDNSGH- 172
            ....::|.|.:|||.|.|:.. ...|:|:|||||.|||||..|.|.|.|:|||||  ..:|:|.
 Frog   262 DPNHWRFQGGKWVPCGKADTNVQGNRVYMHPDSPNTGAHWMRQEISFGKMKLTNNKGASNNNGQM 326

  Fly   173 IVLASMHKYQPRLHVIR-----TADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPF 232
            :||.|:|||||||||:.     |.|.:| | ...|.|.|.||:|:|||||||..||:||||:|||
 Frog   327 VVLQSLHKYQPRLHVVEVNEDGTEDTSQ-P-GRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPF 389

  Fly   233 AKGFR---ETGQSRCK-RKMSSSPTGEDQDQ-SPSLSHS------QSQSESDMSPTK---GGGET 283
            |||||   :|..:.|. .:::.||....:.| .|...:|      |.|..|:.:.::   .|...
 Frog   390 AKGFRDNYDTIYTGCDLDRLTPSPNDSPRSQIVPGARYSMASTFLQDQFVSNYAKSRFHPPGAVP 454

  Fly   284 AGGTSSIGDSDGPQIKRLRSNGSACSLSSSLDDQSVPGASSLALGSPPPHLHSHSHPHP------ 342
            ..||                            |:|||..:.|.   .|........|.|
 Frog   455 GPGT----------------------------DRSVPHTNGLL---SPQQGEDPGAPSPQRWFVT 488

  Fly   343 -----LQARSASSV-FMQHFQQNMQSLLRPSLVDL--------ACT-----YFGRPHEYGGAIQA 388
                 |...|||:. ....|..|..:||..:...:        .||     |:..|..:|.  ::
 Frog   489 PANNRLDFTSASAYDAATDFAGNAATLLSYAAAGVKALPLPGGGCTARPLGYYSDPTGWGA--RS 551

  Fly   389 SPMYPPAAMLQAGLGPHPGLNLPPGVSGADLISDE---SGAEELELDVGSETSTLEQSTQEQPLE 450
            .|.|...:          |..||...:|..:.:..   :|:||:|....::.|.|.:.|:.:.|.
 Frog   552 PPQYCTKS----------GSVLPCWATGGRMAATNPYLTGSEEVESLAATDRSPLGEDTKPKDLS 606

  Fly   451 Q-------PSTRSKGFSISAI 464
            .       ||.:|...|.|.|
 Frog   607 DSSWIETPPSIKSMDSSDSGI 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	T-box_Drosocross-like	56..238	CDD:410332	96/198 (48%)
tbr1	NP_001072587.1	T-box_TBR1	205..395	CDD:410330	95/191 (50%)
		T-box_assoc	420..675	CDD:465042	50/251 (20%)