Protein Alignment Doc2 and tbr1b

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001108562.1
• Gene: tbr1b / 58042
• ZFINID: ZDB-GENE-000323-1
• Length: 676
• Species: Danio rerio
• Alignment Length: 450
• Identity: 150/450 - (33%)
• Similarity: 217/450 - (48%)
• Gaps: 96/450 - (21%)

  Fly    53 LPG-VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRY 116
            :|| .::.|.|..||.:||:..|||||||.||||||.:..::|||:..::|.:.::::......:
Zfish   197 VPGKAQVYLCNRALWLKFHRHQTEMIITKQGRRMFPFLSFNISGLDPTAHYNIFVDVILADPNHW 261

  Fly   117 KFSGSQWVPAGGAEPQ-SPQRMYLHPDSPATGAHWQAQPILFNKVKLTNN--TLDNSGH-IVLAS 177
            :|.|.:|||.|.|:.. :..|:|:|||||.|||||..|.|.|.|:|||||  ..:|:|. :||.|
Zfish   262 RFQGGKWVPCGKADTNVTGNRVYMHPDSPNTGAHWMRQEISFGKLKLTNNKGATNNTGQMVVLQS 326

  Fly   178 MHKYQPRLHVIR-----TADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFR 237
            :|||||||||::     |.|.:| | ...|.|.|.||:|:|||||||..||:||||:||||||||
Zfish   327 LHKYQPRLHVVQVNEDGTEDTSQ-P-GRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFR 389

  Fly   238 ---ETGQSRCK-RKMSSSPTGEDQDQ-SPSLSHS-----------QSQSESDMSPTKGGGETAGG 286
               :|..:.|. .:::.||....:.| .||..::           .|.::|...|..||   |.|
Zfish   390 DNYDTVYTGCDIDRLTPSPGDSPRSQIMPSARYAMTGSFLQDQFVSSYAKSRFHPGVGG---APG 451

  Fly   287 TSSIGDSDGPQIKRLRSNGSACSLSSSLDDQSVPGASSL---------ALGSPPPHLHSHSHPHP 342
            |                            |:|||.::||         .:.||.....:.::...
Zfish   452 T----------------------------DRSVPLSNSLLSPQQTEETTVASPQRWFVTPANNRL 488

  Fly   343 LQARSA-SSVFMQHFQQNMQSLLRPS--------LVDLACT-----YFGRPHEYGGAIQASPMYP 393
            ..|.|| .:.....|..|..:||..:        |....|:     |:|.|..:|  .:..|.|.
Zfish   489 DFAASAYDAAAAADFAGNAATLLSYAAAGVKALPLPGAGCSNRPLGYYGEPPGWG--TRTPPQYC 551

  Fly   394 PAAMLQAGLGPHPGLN--------LPPGVSGADLISDE----SGAEELELDVGSETSTLE 441
            ..:.......|...:.        |.||:...|.|:.|    .||:|.:....||:|.:|
Zfish   552 SKSSSVLSCWPSNSVGSRTTASSYLVPGLEDGDPIAPERSPLGGADESKPKDLSESSWIE 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	98/199 (49%)
tbr1b	NP_001108562.1	TBOX	200..393	CDD:238106	96/194 (49%)
		T-box_assoc	415..673	CDD:292794	47/229 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910