Protein Alignment Doc2 and Tbx21

DIOPT Version :10

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_062380.2
• Gene: Tbx21 / 57765
• MGIID: 1888984
• Length: 530
• Species: Mus musculus
• Alignment Length: 474
• Identity: 150/474 - (31%)
• Similarity: 214/474 - (45%)
• Gaps: 111/474 - (23%)

  Fly    30 PDP-----FPPM--LPIPMPRHVIMP-PR--VTLP-GVEMT------LQNDDLWKQFHQIGTEMI 77
            |.|     :||:  .|.|.||..:.| ||  ..|| |:|::      |.|..||.:|:|..||||
Mouse    93 PPPAGAEGYPPVDGYPAPDPRAGLYPGPREDYALPAGLEVSGKLRVALSNHLLWSKFNQHQTEMI 157

  Fly    78 ITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSP-QRMYLHP 141
            |||.||||||.:..:|:|||..|:|.:.:::|.:....:::...:||..|.||...| .|:|:||
Mouse   158 ITKQGRRMFPFLSFTVAGLEPTSHYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHP 222

  Fly   142 DSPATGAHWQAQPILFNKVKLTNN---TLDNSGHIVLASMHKYQPRLHVIRTADLAQIPWAPQQA 203
            |||.|||||..|.:.|.|:|||||   :.:.:..|||.|:||||||||::...|     ..|:.|
Mouse   223 DSPNTGAHWMRQEVSFGKLKLTNNKGASNNVTQMIVLQSLHKYQPRLHIVEVND-----GEPEAA 282

  Fly   204 --------FVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMSSSPTGEDQDQS 260
                    |.|.||:|:|||||||..||:||||||||||||||..:|.
Mouse   283 CSASNTHVFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRENFESM----------------- 330

  Fly   261 PSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRSNGSACSLSSSLDDQS-----VP 320
                                  .|...:|:....||..:.|..:..:..||:.....|     :|
Mouse   331 ----------------------YASVDTSVPSPPGPNCQLLGGDPFSPLLSNQYPVPSRFYPDLP 373

  Fly   321 G------ASSLALGSPPPHLHSHSHPHPLQARSASSVFMQHFQQNMQSLLRPSLVDLACTYFGRP 379
            |      :....||:|      ..|.:..:.|:.|          |:..|.||.......|: |.
Mouse   374 GQPKDMISQPYWLGTP------REHSYEAEFRAVS----------MKPTLLPSAPGPTVPYY-RG 421

  Fly   380 HEY---GGAIQASPMYPPAAMLQAGLGPHPGLNLPPGVSGADLISDESGAEELELDVGSETSTLE 441
            .:.   |.....:|.|||.........|...|.:.||:..    |:|.|:..   .:..|.::|:
Mouse   422 QDVLAPGAGWPVAPQYPPKMSPAGWFRPMRTLPMDPGLGS----SEEQGSSP---SLWPEVTSLQ 479

  Fly   442 QSTQEQPLEQPSTRSKGFS 460
            ....:..|.:..|:.:..|
Mouse   480 PEPSDSGLGEGDTKRRRIS 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	T-box_Drosocross-like	56..238	CDD:410332	94/199 (47%)
Tbx21	NP_062380.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		T-box_TBX21	135..325	CDD:410329	93/194 (48%)
		T-box_assoc	<393..520	CDD:465042	25/124 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	444..530		12/62 (19%)