Protein Alignment Doc2 and TBX22

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001103348.1
• Gene: TBX22 / 50945
• HGNCID: 11600
• Length: 520
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 141/393 - (35%)
• Similarity: 198/393 - (50%)
• Gaps: 89/393 - (22%)

  Fly    56 VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYK--F 118
            ::|.||..:|||:||.|||||||||:|||||||:|:.|.||:....|.|.:::||:...||:  :
Human    92 IQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVY 156

  Fly   119 SGSQWVPAGGAE-----PQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASM 178
            ..|||:.||..:     |    |.|:|||||.:|..|..|.|.|:::|||||.:|:.|||:|.||
Human   157 HSSQWMVAGNTDHLCIIP----RFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDDKGHIILQSM 217

  Fly   179 HKYQPRLHVIR---TADLAQIPWAPQQ---AFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFR 237
            |||:||:|||.   :.||:||...|.:   .|.|.||||..||||||.:||||||:.||||||||
Human   218 HKYKPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKGFR 282

  Fly   238 ETGQSRCKRKMSSSPTG------EDQDQSPSL--------SHSQSQSESDMSPTKGGGETAG--- 285
            :||::|          |      |.....||.        :.:||.|......|..||..:.
Human   283 DTGRNR----------GVLDGLLETYPWRPSFTLDFKTFGADTQSGSSGSSPVTSSGGAPSPLNS 337

  Fly   286 -------------GTSSIG----DSDGPQI------------------------KRLRSNGSACS 309
                         .|||:|    ::..|.:                        :||.|:.|:.|
Human   338 LLSPLCFSPMFHLPTSSLGMPCPEAYLPNVNLPLCYKICPTNFWQQQPLVLPAPERLASSNSSQS 402

  Fly   310 LSSSLDDQSVPGASSLALGSPPPHLHSHSHPHPLQARSASSVFMQHFQQNMQSLLRPSLVD--LA 372
            |:..:  ..||..|||.:.:........|....|||.::::..:...|......|..|:..  |:
Human   403 LAPLM--MEVPMLSSLGVTNSKSGSSEDSSDQYLQAPNSTNQMLYGLQSPGNIFLPNSITPEALS 465

  Fly   373 CTY 375
            |::
Human   466 CSF 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	105/198 (53%)
TBX22	NP_001103348.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..91
		TBOX	91..287	CDD:238106	105/198 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910