Protein Alignment Doc2 and tbx6

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001007995.1
• Gene: tbx6 / 493357
• XenbaseID: XB-GENE-6257419
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 469
• Identity: 170/469 - (36%)
• Similarity: 226/469 - (48%)
• Gaps: 92/469 - (19%)

  Fly    18 HEIYRQQIM----QRIPDPF------------PPMLPIPMPR------HVIMPPRVT--LPG-VE 57
            ||.||...:    ||....|            ||:.|:.:|.      ..:.||..|  ||| |:
 Frog    33 HEAYRYPELDVPGQRFDGLFPALDPSQRILGAPPLTPLSLPPGPALGFGQLQPPCETPQLPGNVK 97

  Fly    58 MTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSGSQ 122
            |.|:|.:||||||.||||||||||||||||..::||:|||.:..|.:|.::|||.:.|||:...:
 Frog    98 MNLENKELWKQFHSIGTEMIITKSGRRMFPQCKVSVTGLEPDGKYLLLADIVPIDNSRYKWQEDR 162

  Fly   123 WVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQPRLHV 187
            |.|:|.|||:.|:|:|:||||||.|:||..|||.|:|:||||||||..|||:|.||||||||.|:
 Frog   163 WEPSGRAEPRLPERVYIHPDSPAPGSHWMKQPISFHKIKLTNNTLDQMGHIILHSMHKYQPRFHI 227

  Fly   188 IRTADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETG------------ 240
            :|..|:....|....:|.|.||.|:.||||||::||:|||..|||||||||.|
 Frog   228 VRAQDVFSRRWGGCSSFTFPETLFLTVTAYQNEKITQLKIQTNPFAKGFREDGMKSKRDRSTRVK 292

  Fly   241 ---------------QSRCKRKMSSSP----TGEDQDQSPSLSHSQSQSESDMSPTKGGGETAGG 286
                           :..|||.:.:.|    ..|:.|....|.......:....|......|...
 Frog   293 RKVIEPEEEEEEFQPEGECKRPLYTGPCDSTLSEELDIGRGLGIPLPSPDCSFHPITPPSRTPPS 357

  Fly   287 TSSIGDSDGPQIKRLRSNGSACSLSSSLDD-------QSVPGASSLALGS----PPPHLHSHSHP 340
            |    .:..|.:...:..|:|..:||...:       ||.|....:..||    |.....:.:..
 Frog   358 T----QTPNPSLTANQEQGAALEMSSQTPETFLQAAGQSYPEQPPVRGGSLYPCPTDGHGAQNQR 418

  Fly   341 HPLQARSASSVFMQHFQQNMQSLLRPSLVDLACTYFGRPHE---YGGAIQASPMY-PPAAMLQAG 401
            |||..:.....|     |.:|..|..|           |.|   |||.:.....: ||:..:...
 Frog   419 HPLSVQRLPQAF-----QGLQESLGNS-----------PGEYKIYGGDVGCGGDFAPPSCAVAPS 467

  Fly   402 LGPHPGLNLPPGVS 415
            :.|... .||.|.|
 Frog   468 VRPSEE-RLPRGYS 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	113/214 (53%)
tbx6	NP_001007995.1	T-box	100..278	CDD:307177	107/177 (60%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	276..318		7/41 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..418		15/88 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003805
OrthoInspector	1	1.000	-	-		mtm9366
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R6331
SonicParanoid	1	1.000	-	-		X4271
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.040