Protein Alignment Doc2 and Tbx1

DIOPT Version :10

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001402633.1
• Gene: Tbx1 / 360737
• RGDID: 1307734
• Length: 530
• Species: Rattus norvegicus
• Alignment Length: 448
• Identity: 143/448 - (31%)
• Similarity: 204/448 - (45%)
• Gaps: 144/448 - (32%)

  Fly    31 DPFPPMLPIPMPRH-----------VIMPPR----VTLPG------------------------- 55
            |||.|..| |.||:           ...|||    ...||
  Rat    79 DPFGPREP-PPPRYDPCTAAPGAPGPPPPPRAYPFAPAPGAASSSAAESEGPGASRAAAAKAPVK 142

  Fly    56 -------VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGD 113
                   |.:.|:...||.:|:|:|||||:||:||||||:.::.:.|::..::|.:|::.||:.|
  Rat   143 KNPKVASVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDD 207

  Fly   114 CRYK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLA 176
            .||:  |..|.|:.||.|:|.:|.|::.||||||.||.|..|.:.|:|:|||||.||::|||:|.
  Rat   208 KRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHIILN 272

  Fly   177 SMHKYQPRLHVIRT---ADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRE 238
            |||:||||.||:..   .|..:......:.|||.||.|.|||||||.|||:|||.:||||||||:
  Rat   273 SMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGFRD 337

  Fly   239 ------------------TGQSRCKRKMSS--SPTGEDQDQSPSLSHSQSQSESDMSPTKGGGET 283
                              :..:|.:..::|  .|.|.|:|    ::.::.:.:.|..|
  Rat   338 CDPEDWPRNHRPGALPLVSAFARSRNPVASPTQPNGADKD----VAEARREFDRDSGP------- 391

  Fly   284 AGGTSSIGDSDGPQ--IKRLRS-------------NGSACSLSSSLDD--QSVPGASS------- 324
                :::||:..|.  :.|:.|             .||....|....|  ...||||.
  Rat   392 ----AALGDATHPPQLLARVLSPALPGPGGLVPLPGGSGGRHSPPHADLRLEAPGASEPLHHHPY 452

  Fly   325 ----------LALGSPP--------------PHLHSHSHPH--------PLQARSASS 350
                      |...|.|              ||.|.|:|||        |..|.:|::
  Rat   453 KYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHAHPHHHHHPAVNPAAAAAAAA 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	T-box_Drosocross-like	56..238	CDD:410332	95/186 (51%)
Tbx1	NP_001402633.1	T-box_TBX1_10-like	150..337	CDD:410313	95/186 (51%)