DRSC/TRiP Functional Genomics Resources

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Protein Alignment Doc2 and mid

DIOPT Version :10

Sequence 1:NP_648282.1 Gene:Doc2 / 39038 FlyBaseID:FBgn0035956 Length:469 Species:Drosophila melanogaster
Sequence 2:NP_608927.2 Gene:mid / 33770 FlyBaseID:FBgn0261963 Length:580 Species:Drosophila melanogaster


Alignment Length:449 Identity:145/449 - (32%)
Similarity:207/449 - (46%) Gaps:109/449 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 PPMLP---------IPMPRHVIMPPRVT-------LPGVEMTLQNDDLWKQFHQIGTEMIITKSG 82
            ||..|         .|.|  |...|::.       |..|:..|:..:||.:||.:||||||||:|
  Fly   150 PPQSPGTEDSEERLTPEP--VQKAPKIVGSCNCDDLKPVQCHLETKELWDRFHDLGTEMIITKTG 212

  Fly    83 RRMFPSMRLSVSG----LEDESNYCVLLEMVPIGDCRYKFS--GSQWVPAGGAEPQSPQRMYLHP 141
            |||||::|:|.||    ::....|.||::::|:...||:::  .|.|:.||.|:|..|.|:|.||
  Fly   213 RRMFPTVRVSFSGPLRQIQPADRYAVLMDIIPMDSKRYRYAYHRSAWLVAGKADPAPPARLYAHP 277

  Fly   142 DSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQPRLHVIRTADLAQIPWAPQQ---- 202
            |||.:....:.|.|.|.|||||||.:|.:|.|||.|||:||||:|::|.:....||..|::    
  Fly   278 DSPFSCEALRKQVISFEKVKLTNNEMDKNGQIVLNSMHRYQPRIHLVRLSHGQSIPSNPKELQDL 342

  Fly   203 ---AFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMSSSPTGEDQDQSPS-L 263
               .:||.||.|.|||||||..|||||||:||||||||:          ||..|..|:|...: |
  Fly   343 DHKTYVFPETVFTAVTAYQNQLITKLKIDSNPFAKGFRD----------SSRLTDFDRDPMEALL 397

  Fly   264 SHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRSNGSACSLS----------------- 311
            ...|.:|...:.|                  .|.:::..:.|...|::                 
  Fly   398 LEQQLRSPLRLFP------------------DPLMQQFAAQGDPSSMALFEKARQHLQMFGGNSP 444

  Fly   312 -SSLDDQSVPGASSLALGSPPPHLHSHSHPHPLQARSASSVFMQHFQQNMQSLLRPSLVDLACTY 375
             :.|....:..|::.|.|.|||       |..|   .|..:|.|.:.|            |...:
  Fly   445 YAQLMMPQMYQAAAAAAGPPPP-------PPGL---GAFHMFQQQWPQ------------LTAGF 487

  Fly   376 FGRPHEYGGAIQASPM-----YPPAAMLQAGLGPHPGLNLPPGVSGADLISDESGAEEL 429
            ....::...|.||:..     ...||.:.|...|.|    ||..|.....|..|.:.::
  Fly   488 LASANQQAAAAQAAAQAQAQAQAAAAAMAANRTPPP----PPTASTPSSTSSGSPSPDM 542

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Doc2NP_648282.1 T-box_Drosocross-like 56..238 CDD:410332 97/194 (50%)
midNP_608927.2 T-box_TBX20-like 186..382 CDD:410319 98/205 (48%)

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