Protein Alignment Doc2 and bi

DIOPT Version :10

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001259238.1
• Gene: bi / 31379
• FlyBaseID: FBgn0000179
• Length: 1023
• Species: Drosophila melanogaster
• Alignment Length: 610
• Identity: 184/610 - (30%)
• Similarity: 267/610 - (43%)
• Gaps: 179/610 - (29%)

  Fly     9 DLRMQQHIAHEIYRQQIMQRIPDPFPPMLPI----PMPRHVIMPPRVTLPGVEMTLQNDDLWKQF 69
            |:.:...:||:::            |.|.|:    |....|:..|:|||.|       .|||::|
  Fly   296 DVVLASAVAHQLH------------PAMRPLRALQPEDDGVVDDPKVTLEG-------KDLWEKF 341

  Fly    70 HQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSP 134
            |::||||:||||||:|||.|:..||||:.::.|.:||::|...|.||||..|:|:.||.|:|:.|
  Fly   342 HKLGTEMVITKSGRQMFPQMKFRVSGLDAKAKYILLLDIVAADDYRYKFHNSRWMVAGKADPEMP 406

  Fly   135 QRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHI---VLASMHKYQPRLHVIRTADLAQI 196
            :|||:|||||.||..|..:.:.|:|:|||||..|..|.:   :|.||||||||.|::|..|:.::
  Fly   407 KRMYIHPDSPTTGEQWMQKVVSFHKLKLTNNISDKHGFVSTTILNSMHKYQPRFHLVRANDILKL 471

  Fly   197 PWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMS-SSPTGEDQD-- 258
            |::..:.:||.||||:|||||||::||:|||||||||||||:||..:.::|.: .|..|.|.|
  Fly   472 PYSTFRTYVFKETEFIAVTAYQNEKITQLKIDNNPFAKGFRDTGAGKREKKQALMSNRGSDSDKL 536

  Fly   259 -----------------------------------------------QSP--SLSHSQSQSESDM 274
                                                           |||  .||||..|..:..
  Fly   537 NPTHVSSSRAPLHLGHAGRPPHLHPHAALLDNQQDDDDKLLDVVGPPQSPLLPLSHSLQQMHAHQ 601

  Fly   275 SPT-------------KGGGETAGGTSSIGDSDGPQIKRLRSNG--------SACSLS------- 311
            ...             .|..|.|...::...::....:||:::.        |:||.|
  Fly   602 HSAALAAWFNHLAGAGAGASEHAAAAAANASAEDALRRRLQADADVERDGSDSSCSESVGGSTGG 666

  Fly   312 -----SSLDDQSVPGASSLALGS---------------------PPPHLHSHSHPHPLQA----- 345
                 |:...:...||::.|..:                     |.|||..:.:||.|..
  Fly   667 AFRPTSTGSPKEAVGAAAAAAAAGLNPGGGSYPSPNISVGPPIHPSPHLLPYLYPHGLYPPPHLG 731

  Fly   346 ---RSASSVFMQHFQQNMQSLLRPSLVDLACTY---FGRPHEYGGAIQASPM-------YPPAAM 397
               ..|::..|.....|...|....|. ||..:   ||..:...|....||:       :.|.:
  Fly   732 LLHNPAAAAAMSPAGLNPGLLFNAQLA-LAAQHPALFGHAYAAAGHTPVSPLQGLKSHRFSPYS- 794

  Fly   398 LQAGLGP-----HPGLNL-----PPGVSGADLISDESGAEELELDVGSETSTLEQSTQEQPL-EQ 451
            |...||.     .||.|.     |||..|..|     |...:|    :...:|..|.:.:|. ..
  Fly   795 LPGSLGSAFDAVTPGSNANRSGDPPGGGGGGL-----GGGVVE----NGPRSLSSSPRPRPASHS 850

  Fly   452 PSTRSKGFS-------ISAILGGGS 469
            |.||....|       :....|||:
  Fly   851 PPTRPISMSPTTPPSLMKQPRGGGA 875

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	T-box_Drosocross-like	56..238	CDD:410332	99/184 (54%)
bi	NP_001259238.1	Optomotor-blind	<260..318	CDD:337907	6/33 (18%)
		T-box_TBX2_3-like	326..513	CDD:410314	104/193 (54%)