Protein Alignment Doc2 and tbx4

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_570989.2
• Gene: tbx4 / 30070
• ZFINID: ZDB-GENE-991124-5
• Length: 543
• Species: Danio rerio
• Alignment Length: 388
• Identity: 147/388 - (37%)
• Similarity: 208/388 - (53%)
• Gaps: 46/388 - (11%)

  Fly    49 PRVTLPGVEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGD 113
            |..::..:::.|.:.:|||:||:.||||||||:|||||||.::.|:|:..::.|.:|.::||..|
Zfish    46 PDQSIENIKVVLHDRELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLTDIVPADD 110

  Fly   114 CRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASM 178
            .||||..::|:.||.|||..|.|:|:|||||||||||..|.:.|.|:|||||.||..|||:|.||
Zfish   111 HRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSM 175

  Fly   179 HKYQPRLHVIRTADLAQIPWAPQQAF---VFAETEFVAVTAYQNDRITKLKIDNNPFAKGFR--E 238
            ||||||||::: ||......:...|:   ||.||.|::||:|||.:||:|||:|||||||||  :
Zfish   176 HKYQPRLHIVK-ADENNAFGSKNTAYCTHVFHETAFISVTSYQNHKITQLKIENNPFAKGFRGSD 239

  Fly   239 TGQSRCKRKMSSSPTGEDQDQSPSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRS 303
            .|..|..|..     |:|.   |.:|.:..:.....|.....|:.:.|..    |..||:.....
Zfish   240 EGDLRVSRLQ-----GKDY---PVISKNMVRQRLISSHGHLSGKLSAGVL----SSHPQVLSHYQ 292

  Fly   304 NGSACSLSSSLDDQSVPGASSLALGSPPPHLHSHSHPH-------------PLQARSASSVFMQH 355
            ..|...|.:| |.|.  ..|:....|..|.|..|...|             |....::|:|..:|
Zfish   293 YDSGVPLPNS-DSQE--ALSNSFTSSREPSLLYHCFKHRDNPRHLELGCKRPYLDTTSSAVSEEH 354

  Fly   356 FQQNMQSLLRPSLVD----------LACTYFGRPHEYGGAIQASPMYPPA--AMLQAGLGPHP 406
            :.::..|...|.|..          .||.|.|...|.|||:....:..|:  ..:.|.:.|:|
Zfish   355 YFRSPPSYDSPLLSHPYCNEALGSREACMYGGLEGEGGGAVGTDDLPAPSLNCNMWASVQPYP 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	104/191 (54%)
tbx4	NP_570989.2	TBOX	52..240	CDD:238106	103/188 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.910