DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Doc2 and tbx-7

DIOPT Version :9

Sequence 1:	NP_648282.1	Gene:	Doc2 / 39038	FlyBaseID:	FBgn0035956	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	NP_001368540.1	Gene:	tbx-7 / 260030	WormBaseID:	WBGene00006544	Length:	335	Species:	Caenorhabditis elegans

Alignment Length:	225	Identity:	107/225 - (47%)
Similarity:	139/225 - (61%)	Gaps:	9/225 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 PGVEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKF 118
            |.||  |.|.:||..|.:.||||||||.||||||.::|.:|||:..|||.:::||:.:...||||
Worm    64 PNVE--LVNRNLWSTFLECGTEMIITKKGRRMFPLVKLKLSGLDKNSNYTIIMEMISVDKLRYKF 126

  Fly   119 SGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQP 183
            ....|:.||..|.......::||.||.:|..|....:.|...||:||..:|.|||||.|||:|.|
Worm   127 WNGNWIVAGVGEHHPLPTCFVHPQSPRSGEWWMTDGVDFKMAKLSNNPFNNDGHIVLNSMHRYNP 191

  Fly   184 RLHVIRTADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKM 248
            |.|::|.....|...|..:.|.|.||||:||||||||.:||.||||||||||||.....| ||||
Worm   192 RFHIVRADSSGQPILASLKTFSFKETEFIAVTAYQNDVVTKCKIDNNPFAKGFRNIDTVR-KRKM 255

  Fly   249 ----SSSPTGEDQDQSPSLSHSQSQSESDM 274
                |:.|..||::  |.:..::|:.|:.|
Worm   256 NQIISTPPASEDEE--PEVKRTKSEIEAVM 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	93/186 (50%)
tbx-7	NP_001368540.1	T-box	66..245	CDD:395727	91/180 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003805
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910