Protein Alignment Doc2 and Tbx22

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_851836.2
• Gene: Tbx22 / 245572
• MGIID: 2389465
• Length: 531
• Species: Mus musculus
• Alignment Length: 447
• Identity: 149/447 - (33%)
• Similarity: 211/447 - (47%)
• Gaps: 99/447 - (22%)

  Fly    56 VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYK--F 118
            :::.||..||||:||.|||||||||:|||||||:|:.|.|::....|.|:|::||:...||:  :
Mouse   103 IQVELQGSDLWKRFHDIGTEMIITKAGRRMFPSVRIKVKGMDPVKQYYVILDVVPVDSKRYRYVY 167

  Fly   119 SGSQWVPAGGAEPQ--SPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKY 181
            ..|||:.||..:..  :| |.|:|||||.:|.:|..|.|.|::||||||.:|:.|||:|.|||||
Mouse   168 HSSQWMVAGNTDHSCITP-RFYVHPDSPCSGENWMRQIISFDRVKLTNNEMDDKGHIILQSMHKY 231

  Fly   182 QPRLHVIR---TADLAQIPWAPQQ---AFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETG 240
            .||:||:.   ..||:.|...|.:   .|.|.||||..||||||.:|||||||.||||||||:.|
Mouse   232 NPRVHVVEQDSRIDLSLIESFPTEGVKTFSFKETEFTTVTAYQNQQITKLKIDRNPFAKGFRDPG 296

  Fly   241 QSRCKRKMSSSPTG------EDQDQSPSLS--------HSQSQSESDMSPTKGGGETAGGTSSIG 291
            ::|          |      |.....||.|        .:||.|......|..||..:...|.:.
Mouse   297 RNR----------GVLDGFLETYPWMPSFSMDFKTFVTDTQSGSSGSSPVTSSGGAPSPLNSLLS 351

  Fly   292 DSDGPQIKRLRSNGSACS-----------------------------------LSSSLDDQS--- 318
            .|..|.:..:..:....:                                   |.|.:..|:
Mouse   352 PSCSPPMVYIPPSSFGMTYPDAYLHSVNIPFCYRICPTNNWRSQPFVLPTPERLPSFIIPQTLPP 416

  Fly   319 ----VPGASSLALGSPPPHLHSHSHPHPLQARSASSVFMQHFQQNMQSLLRP-SLVDLACTYFGR 378
                ||..||..:.:|...||...:...||| |.|:..|.:..||..::..| ::...|.:|
Mouse   417 LMMEVPVVSSRGIINPNSGLHEDCNGQCLQA-SHSANQMLYGLQNPGNIFHPNAIAQEAISY--- 477

  Fly   379 PHEYGGAIQASPMYPPAAMLQAGLGPHPGLNLPPGVSGADLISDESGAEELELDVGS 435
                       |.:||....:.      .:::||.:........|:|..::....||
Mouse   478 -----------PFHPPNGCYRY------TISMPPRLENVASHLSENGTSQISFTEGS 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	104/195 (53%)
Tbx22	NP_851836.2	TBOX	103..298	CDD:238106	104/195 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910