Protein Alignment Doc2 and Tbx5

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: XP_006530342.1
• Gene: Tbx5 / 21388
• MGIID: 102541
• Length: 537
• Species: Mus musculus
• Alignment Length: 468
• Identity: 156/468 - (33%)
• Similarity: 213/468 - (45%)
• Gaps: 130/468 - (27%)

  Fly    53 LPGVEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYK 117
            :.|:::.|...:||.:||::||||||||:|||||||.::.|:||..::.|.:|:::||..|.|||
Mouse    70 MEGIKVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRYK 134

  Fly   118 FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQ 182
            |:.::|...|.|||..|.|:|:|||||||||||..|.:.|.|:|||||.||..|||:|.||||||
Mouse   135 FADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFGHIILNSMHKYQ 199

  Fly   183 PRLHVIRTADLAQIPWAPQQAF---VFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRC 244
            ||||::: ||......:...||   ||.||.|:|||:|||.:||:|||:|||||||||
Mouse   200 PRLHIVK-ADENNGFGSKNTAFCTHVFPETAFIAVTSYQNHKITQLKIENNPFAKGFR------- 256

  Fly   245 KRKMSSSPTGEDQDQSPSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRSNGSACS 309
                     |.|..:...:|..||: |..:.|          .|::............|...|.|
Mouse   257 ---------GSDDLELHRMSRMQSK-EYPVVP----------RSTVRHKVTSNHSPFSSETRALS 301

  Fly   310 LSSSLDDQ-----SVPGASSLALGSPPPH--LHSHS-----------------HPH--PLQARSA 348
            .||:|..|     .|.|.|...|..|.|:  ...||                 ||:  |....|.
Mouse   302 TSSNLGSQYQCENGVSGPSQDLLPPPNPYPLAQEHSQIYHCTKRKDEECSSTEHPYKKPYMETSP 366

  Fly   349 S-------SVFMQHFQQNMQSLLR---------------------PSLVDLAC-TYFGRP----- 379
            |       |.:.|  ||.:.:..|                     |||.|::| |:...|
Mouse   367 SEEDTFYRSGYPQ--QQGLSTSYRTESAQRQACMYASSAPPSEPVPSLEDISCNTWPSMPSYSSC 429

  Fly   380 -------------HEYGGAIQASPMYPPAA--------MLQAGL----------------GPHPG 407
                         ..:.....:.|:.|..|        .|..|:                ||..|
Mouse   430 TVTTVQPMDRLPYQHFSAHFTSGPLVPRLAGMANHGSPQLGEGMFQHQTSVAHQPVVRQCGPQTG 494

  Fly   408 LNLPPGVSGADLI 420
            |..|.|:...:.:
Mouse   495 LQSPGGLQPPEFL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	105/189 (56%)
Tbx5	XP_006530342.1	TBOX	72..260	CDD:238106	106/204 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910