Protein Alignment Doc2 and Tbx3

DIOPT Version :10

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_035665.2
• Gene: Tbx3 / 21386
• MGIID: 98495
• Length: 741
• Species: Mus musculus
• Alignment Length: 520
• Identity: 160/520 - (30%)
• Similarity: 229/520 - (44%)
• Gaps: 152/520 - (29%)

  Fly    21 YRQQIMQRIPD-----------PFPPMLPIP--------MPRHVIMPPRVTLPGVEMT------- 59
            |...:..|.||           ||.|.|.:|        :|..:..|....|.|...|
Mouse    17 YHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSL 81

  Fly    60 -------------------------LQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDE 99
                                     |:..:||.|||:.||||:||||||||||..::..|||:.:
Mouse    82 GPQAHLRPLKTMEPEEDVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKK 146

  Fly   100 SNYCVLLEMVPIGDCRYKFSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTN 164
            :.|.:|::::...||||||..|:|:.||.|:|:.|:|||:||||||||..|.::.:.|:|:||||
Mouse   147 AKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTN 211

  Fly   165 NTLDNSG--------------------HIVLASMHKYQPRLHVIRTADLAQIPWAPQQAFVFAET 209
            |..|..|                    ..:|.||||||||.|::|..|:.::|::..:.::|.||
Mouse   212 NISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPET 276

  Fly   210 EFVAVTAYQNDRITKLKIDNNPFAKGFRETG------------------QSRCKRKMSSSPTGED 256
            ||:||||||||:||:|||||||||||||:||                  :.|.|::.|...:.|.
Mouse   277 EFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFEERHKKETSDESSSEQ 341

  Fly   257 -------QDQSPSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDGPQIKRLRSNGSACSLSS-S 313
                   |..||::|...:.:..|:.|::...:....:.   :..||:         ||..:. |
Mouse   342 AAFNCFAQASSPAVSIVGTSNLKDLCPSEAESDAEAESK---EEHGPE---------ACDAAKIS 394

  Fly   314 LDDQSVPGASSLALGSPPPHLHSHSHP-HPLQARSA-----SSVFMQHFQQNMQSLLR------- 365
            ......||...   |||.  ..:...| .|.:||..     :|...:|....:.|..|
Mouse   395 TTTAEEPGRDK---GSPA--TRAQLFPAEPSRARDTARLDKASPDSRHSPATISSSTRVPGADER 454

  Fly   366 ---------PSLVDLACTYFGRPHEYGGAIQASPMYPPA-----AMLQAGLGPHPGLNLPPGVSG 416
                     .:.||.|           .||.|...:.|.     |......||.|||...||::|
Mouse   455 RSPGREGPVATKVDEA-----------RAIPAKDAFAPLSVQTDATAHLAQGPLPGLGFAPGLAG 508

  Fly   417  416
            Mouse   509  508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	T-box_Drosocross-like	56..238	CDD:410332	100/233 (43%)
Tbx3	NP_035665.2	T-box_TBX2_3-like	101..305	CDD:410314	99/203 (49%)
		TBX	323..402	CDD:432659	15/90 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	369..469		19/116 (16%)