Protein Alignment Doc2 and Tbx15

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_033349.2
• Gene: Tbx15 / 21384
• MGIID: 1277234
• Length: 602
• Species: Mus musculus
• Alignment Length: 494
• Identity: 166/494 - (33%)
• Similarity: 232/494 - (46%)
• Gaps: 91/494 - (18%)

  Fly    56 VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYK--F 118
            :::.||..||||:||.|||||||||:||||||:||:.::||:....|.:.:::||:.:.||:  :
Mouse   113 IQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDNKRYRYVY 177

  Fly   119 SGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQP 183
            ..|:|:.||.|:...|.|:|:||||.|:|..|..|.:.|:|:|||||.||:.|||:|.|||||||
Mouse   178 HSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQGHIILHSMHKYQP 242

  Fly   184 RLHVIR---TADLAQIPWAP----QQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQ 241
            |:||||   ::||:.....|    .:.|.|.||.|..||||||.:||:||||.||||||||::|:
Mouse   243 RVHVIRKDFSSDLSPTKPVPVGDGVKTFNFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGR 307

  Fly   242 SR--------------------------CKRKMSSSPTGEDQDQSPSLSHSQSQSESDMSPTKGG 280
            :|                          ..:|.....||.....|.:.:.|.|.|...:||:...
Mouse   308 NRTGLEAIMETYAFWRPPVRTLTFEDFTTMQKQQGGSTGTSPTTSSTGTPSPSASSHLLSPSCSP 372

  Fly   281 G--ETAGGTSSIGDSDGPQIKRLRSNGSACSLSSSLDDQSVPGAS-------------------- 323
            .  ..|..|.::|..:........|:...|:.|:....||.||.|
Mouse   373 PTFHLAPNTFNVGCRESQLCNLNLSDYPPCARSNMAALQSYPGLSDSGYNRLQSGTASATQPSET 437

  Fly   324 -------SLALGSP-PPHLHSHSHPHPLQARSASSVFMQHFQQNMQSLLRPSLVDLACTYFGRPH 380
                   ||..|.| ||.|.|:|.......:..|....| ||..||:       ..|.:....||
Mouse   438 FMPQRTPSLISGIPTPPSLPSNSKMEAYGGQLGSFPTSQ-FQYVMQA-------GNAASSSSSPH 494

  Fly   381 EYGG------AIQASPMYPPAAMLQAGLGPHPGLNLPP---GVSGADLI--SDESGA--EELELD 432
            .:||      :..|..::.|..:........|.|...|   ..|.:.|:  |..:||  |...|.
Mouse   495 MFGGSHMQQSSYNAFSLHNPYNLYGYNFPTSPRLAASPEKLSASQSTLLCSSPSNGAFGERQYLP 559

  Fly   433 VGSETS--TLEQSTQEQPLEQPSTRSKGFSISAILGGGS 469
            .|.|.|  .:..||..|   |.:....|....|:.|..|
Mouse   560 TGMEHSMHMISPSTNNQ---QATNTCDGRQYGAVPGSAS 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	102/194 (53%)
Tbx15	NP_033349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	43..95
		TBOX	113..308	CDD:238106	102/194 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	338..369		8/30 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	425..444		0/18 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910