Protein Alignment Doc2 and Tbx1

DIOPT Version :9

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001360867.1
• Gene: Tbx1 / 21380
• MGIID: 98493
• Length: 529
• Species: Mus musculus
• Alignment Length: 450
• Identity: 142/450 - (31%)
• Similarity: 202/450 - (44%)
• Gaps: 149/450 - (33%)

  Fly    31 DPFPPMLPIPMPRHVIMPPRVTLPG---------------------------------------- 55
            |||.|..| |.||:   .|...:||
Mouse    79 DPFGPREP-PPPRY---DPCAAVPGAPGPPPPRAYPFAPAPGAAGSSAAESEGPGASRAAAVKAP 139

  Fly    56 ---------VEMTLQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPI 111
                     |.:.|:...||.:|:|:|||||:||:||||||:.::.:.|::..::|.:|::.||:
Mouse   140 VKKNPKVASVSVQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPV 204

  Fly   112 GDCRYK--FSGSQWVPAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIV 174
            .|.||:  |..|.|:.||.|:|.:|.|::.||||||.||.|..|.:.|:|:|||||.||::|||:
Mouse   205 DDKRYRYAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNGHII 269

  Fly   175 LASMHKYQPRLHVIRT---ADLAQIPWAPQQAFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGF 236
            |.|||:||||.||:..   .|..:......:.|||.||.|.|||||||.|||:|||.:|||||||
Mouse   270 LNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFTAVTAYQNHRITQLKIASNPFAKGF 334

  Fly   237 RE------------------TGQSRCKRKMSS--SPTGEDQDQSPSLSHSQSQSESDMSPTKGGG 281
            |:                  :..:|.:..::|  .|.|.|:|.      ::::.|.|..
Mouse   335 RDCDPEDWPRNHRPGALPLVSAFARSRNPVASPTQPNGSDKDA------AEARREFDRD------ 387

  Fly   282 ETAGGTSSIGDSDGPQ--IKRLRS-------------NGSACSLSSSLDD--QSVPGASS----- 324
               .|.:::||:..|.  :.|:.|             .||....|....|  ...||||.
Mouse   388 ---SGPAALGDATHPPQLLARVLSPALPGPGGLVPLPGGSGGRHSPPHADLRLEAPGASEPLHHH 449

  Fly   325 ------------LALGSPP--------------PHLHSHSHPH--------PLQARSASS 350
                        |...|.|              ||.|.|:|||        |..|.:|::
Mouse   450 PYKYPAAAYDHYLGAKSRPAPYPLPGLRGHGYHPHAHPHAHPHHHHHPAVNPAAAAAAAA 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	TBOX	55..242	CDD:238106	97/258 (38%)
Tbx1	NP_001360867.1	T-box	151..336	CDD:366363	94/184 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3585
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11267
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910