Protein Alignment Doc2 and T

DIOPT Version :10

• Sequence 1: NP_648282.1
• Gene: Doc2 / 39038
• FlyBaseID: FBgn0035956
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_033335.1
• Gene: T / 20997
• MGIID: 98472
• Length: 436
• Species: Mus musculus
• Alignment Length: 406
• Identity: 133/406 - (32%)
• Similarity: 189/406 - (46%)
• Gaps: 113/406 - (27%)

  Fly    60 LQNDDLWKQFHQIGTEMIITKSGRRMFPSMRLSVSGLEDESNYCVLLEMVPIGDCRYKFSGSQWV 124
            |:..:||.:|.::..|||:||:||||||.::::||||:..:.|..||:.|...:.|:|:...:||
Mouse    46 LEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLLDFVTADNHRWKYVNGEWV 110

  Fly   125 PAGGAEPQSPQRMYLHPDSPATGAHWQAQPILFNKVKLTNNTLDNSGHIVLASMHKYQPRLHVIR 189
            |.|..|||:|..:|:|||||..||||...|:.|:||||||. |:..|.|:|.|:|||:||:|::|
Mouse   111 PGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNK-LNGGGQIMLNSLHKYEPRIHIVR 174

  Fly   190 TADLAQIPWAPQQ---AFVFAETEFVAVTAYQNDRITKLKIDNNPFAKGFRETGQSRCKRKMSSS 251
            ..       .||:   :..|.||:|:|||||||:.||.|||..|||||.|.:..:....:.:...
Mouse   175 VG-------GPQRMITSHCFPETQFIAVTAYQNEEITALKIKYNPFAKAFLDAKERNDHKDVMEE 232

  Fly   252 PTGEDQDQS----------------PSLSHSQSQSESDMSPTKGGGETAGGTSSIGDSDG----P 296
            | |:.|...                |:.||.|                .||:.|:..:.|    |
Mouse   233 P-GDCQQPGYSQWGWLVPGAGTLCPPASSHPQ----------------FGGSLSLPSTHGCERYP 280

  Fly   297 QIKRLRS------------------NGSAC-SLSSSLDDQS---VPGASSLA----LGSPP---- 331
            .::..||                  |.||| |:..|.|:.|   |||.:|:.    ..|||
Mouse   281 ALRNHRSSPYPSPYAHRNSSPTYADNSSACLSMLQSHDNWSSLGVPGHTSMLPVSHNASPPTGSS 345

  Fly   332 --PHLHSHSH----PHPLQARSASSVFMQHFQQNMQSLLRPSLVDLACTYFGRPHEY-------- 382
              |.|.|.|:    |....|..::.:..|.|:                   |.|..|
Mouse   346 QYPSLWSVSNGTITPGSQTAGVSNGLGAQFFR-------------------GSPAHYTPLTHTVS 391

  Fly   383 --GGAIQASPMYPPAA 396
              ..:...||||..||
Mouse   392 AATSSSSGSPMYEGAA 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Doc2	NP_648282.1	T-box_Drosocross-like	56..238	CDD:410332	87/180 (48%)
T	NP_033335.1	T-box_TBXT	41..219	CDD:410328	87/180 (48%)